Results 121 to 130 of about 606,278 (266)

In vivo Testing of Nanotherapeutics for Osteosarcoma Treatment: Translational Challenges and Solutions. [PDF]

Int J Nanomedicine
D'Anna G, Hanurry EY, Piperno A, Scala A.   +3 more
europepmc   +1 more source

Carrier-free nanoparticles of camptothecin prodrug for chemo-photothermal therapy: the making, in vitro and in vivo testing. [PDF]

J Nanobiotechnology, 2021
Ao M, Yu F, Li Y, Zhong M, Tang Y, Yang H, Wu X, Zhuang Y, Wang H, Sun X, Hong X, Chen XD.   +11 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Development and Pilot in Vivo Testing of a Protocol for PLGA-Vancomycin Coatings on PTFE Used as Silicone-Implant Analogs. [PDF]

Medicina (Kaunas)
Negrilă AA, Nica O, Ciocîlteu MV, Bită A, Nicolicescu C, Popescu AB, Ciurea ME.   +6 more
europepmc   +1 more source

Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR. [PDF]

Genes Environ, 2023
Furihata C, Suzuki T.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The development, validation, and in vivo testing of a high-precision bronchial epithelial lining fluid sampling device. [PDF]

Front Med (Lausanne), 2023
Gupta A, Burgess JK, Slebos DJ, Pouwels SD.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Technique For Testing Drug-coated Balloons In Deep Veins In Vivo

JVS - Vascular Science, 2023
Oscar Y. Moreno Rocha, Kiran Kumar, Sabrina Rocco, Sriganesh Sharma, Catherine Luke, Laura Durham, Amber Clay, Sharika Bamezai, Daniel D. Myers, Jr., Thomas Wakefield, Peter Henke, Andrea T. Obi   +11 more
doaj   +1 more source

Design Features of a Titanium Mesh for Guided Bone Regeneration and In Vivo Testing in Vitamin D3 Deficiency Condition. [PDF]

Biomimetics (Basel)
Diachkova E, Kazumova A, Shamanaev A, Shcherbinina L, Gulyaev A, Vasil'ev Y, Petruk P, Brago A, Enina Y, Chilikov V, Darawsheh H, Makeeva E, Tarasenko S.   +12 more
europepmc   +1 more source