Results 131 to 140 of about 606,278 (266)

Rational Design of Self-Emulsifying Pellet Formulation of Thymol: Technology Development Guided by Molecular-Level Structure Characterization and Ex Vivo Testing. [PDF]

Pharmaceutics, 2022
Macku J, Kubova K, Urbanova M, Muselik J, Franc A, Koutna G, Pavelkova M, Vetchy D, Masek J, Maskova E, Brus J.   +10 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

In Vitro and In Vivo Testing of Decellularized Lung and Pancreas Matrices as Potential Islet Platforms. [PDF]

Int J Mol Sci
Bogomolova A, Ermakova P, Potapov A, Mozherov A, Tselousova J, Vasilchikova E, Kashina A, Zagaynova E.   +7 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Isolation and Ex Vivo Testing of CD8⁺ T-Cell Division and Activation Using Mouse Splenocytes. [PDF]

Bio Protoc
Dolan M, Shi Y, McKenery A, Tzetzo S, Chida K, Takabe K, Abrams SI, Ebos JML.   +7 more
europepmc   +1 more source

Biogenic Ferrihydrite Nanoparticles: Synthesis, Properties In Vitro and In Vivo Testing and the Concentration Effect. [PDF]

Biomedicines, 2021
Stolyar SV, Kolenchukova OA, Boldyreva AV, Kudryasheva NS, Gerasimova YV, Krasikov AA, Yaroslavtsev RN, Bayukov OA, Ladygina VP, Birukova EA.   +9 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs. [PDF]

Nat Commun
Brancucci NMB, Gumpp C, van Gemert GJ, Yu X, Passecker A, Nardella F, Thommen BT, Chambon M, Turcatti G, Halby L, Blasco B, Duffey M, Arimondo PB, Bousema T, Scherf A, Leroy D, Kooij TWA, Rottmann M, Voss TS.   +18 more
europepmc   +1 more source

Rhenium-Based Complexes and in Vivo Testing: A Brief History. [PDF]

Chembiochem, 2020
Capper MS, Packman H, Rehkämper M.
europepmc   +1 more source

Amorphous Solid Dispersions and the Contribution of Nanoparticles to In Vitro Dissolution and In Vivo Testing: Niclosamide as a Case Study. [PDF]

Pharmaceutics, 2021
Jara MO, Warnken ZN, Williams RO.
europepmc   +1 more source