Results 141 to 150 of about 606,278 (266)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Fabrication and in vivo testing of a sub-mm duckbill valve for hydrocephalus treatment. [PDF]

Microsyst Nanoeng
Jung Y, Gulick D, Blain Christen J.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Characterisation of iatrogenic human ureteral laser injury - results from ex vivo testing with a Ho: YAG laser at commonly used lithotripsy settings. [PDF]

World J Urol
O'Meara S, Sheehan K, Fay J, O'Grady T, Croghan SM, Cunnane EM, Hogan D, Calpin GG, Somani B, Walsh MT, O'Brien FJ, Davis NF.   +11 more
europepmc   +1 more source

Preliminary study on modelling, fabrication by photo-chemical etching and in vivo testing of biodegradable magnesium AZ31 stents. [PDF]

Bioact Mater, 2021
Kandala BSPK, Zhang G, LCorriveau C, Paquin M, Chagnon M, Begun D, Shanov V.   +6 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Design and In Vivo Testing of an Anatomic 3D-Printed Peripheral Nerve Conduit in a Rat Sciatic Nerve Model. [PDF]

HSS J
Chang PS, Lee TY, Kneiber D, Dy CJ, Ward PM, Kazarian GS, Apostolakos J, Brogan DM.   +7 more
europepmc   +1 more source

Polyurethane derived from castor oil monoacylglyceride (Ricinus communis) for bone defects reconstruction: characterization and in vivo testing. [PDF]

J Mater Sci Mater Med, 2021
de Morais JPP, Pacheco IKC, Filho ALMM, Ferreira DCL, Viana FJC, da Silva Reis F, de Matos JME, Dos Santos Rizzo M, Fialho ACV.   +8 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Onward to Better Surgery - the Critical Need for Improved Ex Vivo Testing and Training Methods. [PDF]

Proc SPIE Int Soc Opt Eng
Henderson ER, Halter R, Paulsen KD, Pogue BW, Elliott J, LaRochelle E, Ruiz A, Jiang S, Streeter SS, Samkoe KS, Gibbs S.   +10 more
europepmc   +1 more source