Results 91 to 100 of about 156,029 (310)

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Efficacy of an experimental E. coli inactivated vaccine in turkey poults

Journal of Applied Veterinary Sciences, 2016
E. coli infections are responsible for great economic losses in the poultry industry worldwide, bringing serious threat to the turkey industry. The present investigation aimed to prepare a potent vaccine from E.
Gina M. Mohammed, Shell W.S., Sayed M.L. , Ibrahim H.M. , Hanan M.H. , Ghada M. El-Sadek   +5 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Assessment of mycoplasma vaccine efficacy in reducing infection with Newcastle disease virus

VacciMonitor, 2023
The present work recorded the impact of using Mycoplasma gallisepticum vaccines on post-vaccinal response and protection against challenge with Newcastle disease virus. Specific pathogen-free chickens were divided into eight groups of forty chickens each.
Hala Mahmoud, Marwa Fathy Elsayed, Reem A. Soliman, Mounir El Safty, Moustafa A. Zaghloul   +4 more
doaj  

Preparation and immune in chickens of pulsatile delivery system for inactivated Newcastle disease vaccine

Asian Pacific Journal of Tropical Medicine, 2018
Due to the weak immunogenicity, traditional inactivated vaccines need to use adjuvants and multiple doses to generate effective immune protection. Therefore, in theory and practice, it is valuable to develop a vaccine delivery system with an adjuvant ...
Jun Li
doaj   +1 more source

SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]

, 2012
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R, Bruzzone, R, Cheung, CY, Daeron, M, Dutry, I, Escriou, N, Jaume, M, Kam, YW, Kien, F, Li, PH, Nal, B, Peiris, JSM, Roberts, A, Subbarao, K, Yip, MS   +14 more
core   +1 more source

The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees? [PDF]

, 2017
Could new oral vaccine technologies protect endangered wildlife against a rising tide of infectious disease? We used captive chimpanzees to test oral delivery of a rabies virus (RABV) vectored vaccine against Ebola virus (EBOV), a major threat to wild ...
Goetzmann, Jason E., Hasselschwert, Dana L., Kurup, Drishya, Schnell, Matthias J., Walsh, Peter D., Wirblich, Christoph   +5 more
core   +2 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Five-year antibody persistence in children after one dose of inactivated or live attenuated hepatitis A vaccine

Human Vaccines & Immunotherapeutics, 2017
In China, both inactivated hepatitis A (HA) vaccine and live attenuated HA vaccine are available. We conducted a trial to evaluate 5-year immune persistence induced by one dose of inactivated or live attenuated HA vaccines in children.
Zhilun Zhang, Xiangjun Zhu, Yuansheng Hu, Miao Liang, Jin Sun, Yufei Song, Qi Yang, Haiquan Ji, Gang Zeng, Lifei Song, Jiangting Chen   +10 more
doaj   +1 more source

Prime-boost vaccination with attenuated Salmonella Typhimurium ΔznuABC and inactivated Salmonella Choleraesuis is protective against Salmonella Choleraesuis challenge infection in piglets

BMC Veterinary Research, 2017
Background Salmonella enterica serovar Choleraesuis (S. Choleraesuis) infection causes a systemic disease in pigs. Vaccination could represent a solution to reduce prevalence in farms.
Giovanni Loris Alborali, Jessica Ruggeri, Michele Pesciaroli, Nicola Martinelli, Barbara Chirullo, Serena Ammendola, Andrea Battistoni, Maria Cristina Ossiprandi, Attilio Corradi, Paolo Pasquali   +9 more
doaj   +1 more source