Naringenin as a phytogenic adjuvant systematically enhances the protective efficacy of H9N2 inactivated vaccine through coordinated innate-adaptive immune priming in chickens. [PDF]
Jiao L +10 more
europepmc +1 more source
Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz +24 more
wiley +1 more source
Immunogenicity of a novel HMT13 adjuvant-based inactivated vaccine against Avian pathogenic Escherichia coli serogroups O36, O78, and O109. [PDF]
Jia C +7 more
europepmc +1 more source
ABSTRACT Background The 2023 SARS‐CoV‐2 environment differs greatly from the initial outbreak, with new variants and widespread vaccination. Early in the pandemic, blood group A was linked to increased hospitalisation and poor outcomes, but its role now, since the availability of vaccination, is unclear.
Alice Hathaway +66 more
wiley +1 more source
Intranasally administered whole virion inactivated vaccine against clade 2.3.4.4b H5N1 influenza virus with optimized antigen and increased cross-protection. [PDF]
Song JH +7 more
europepmc +1 more source
ABSTRACT Covalently closed circular DNA (cccDNA) represents the central obstacle to achieving a functional cure for chronic hepatitis B virus (HBV) infection. Poly6, a peptide encoded within the HBV genome, was investigated for antiviral efficacy in hepatocyte‐derived cell lines, hydrodynamic injection models, and HBV transgenic mice.
Junghwa Jang +5 more
wiley +1 more source
Immunological Responses and Protection in the Largemouth Bass (<i>Microterus salmoides</i>) Immunized with Inactivated Vaccine Against Largemouth Bass Ranavirus (LMBRaV). [PDF]
Yang T +10 more
europepmc +1 more source
This study identified covert infection of MPXV among people living with HIV and MPXV‐IgA was the effective indicator. The combined use of two antigen protein set of MPXV (B6R plus E8L and E8L plus H3L) yield IgA test results comparable to those obtained with the MPXV.
Rui Song +12 more
wiley +1 more source
The Influence of the Associated Inactivated Vaccine Against Infectious Rhinotracheitis and Bovine Viral Diarrhea on the Formation and Duration of Colostral Immunity in Kazakh Whiteheaded Calves. [PDF]
Bulatov Y +16 more
europepmc +1 more source
Isocitrate Dehydrogenase‐Mutant Astrocytomas: Risk Stratification and Therapeutic Advance
This graphical abstract synthesizes the core logic of our revised review by linking integrated diagnosis, risk stratification, and trajectory‐based management in IDH‐mutant astrocytomas across CNS WHO Grades 2–4. It highlights lineage‐defining molecular classification (IDH mutation with core co‐alterations), integrated histomolecular grading, and key ...
Shepeng Wei +3 more
wiley +1 more source

