Results 71 to 80 of about 156,029 (310)

Efficacy of H2O2 inactivated bovine virus diarrhoea virus (BVDV) type 1 vaccine in mice

BMC Veterinary Research
Background Bovine viral diarrhea (BVD) is an acute febrile infectious disease caused by the bovine viral diarrhea virus (BVDV), which has brought huge economic losses to the world's cattle industry.
Cunyuan Li, Jinming Yu, Yue Wang, Xiaoyue Li, Yaxin Li, Mingxuan An, Wei Ni, Kaiping Liu, Shengwei Hu   +8 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease. [PDF]

PLoS ONE, 2011
Respiratory syncytial virus (RSV) is a leading cause of bronchiolitis and pneumonia in young children worldwide, and no vaccine is currently available.
Dennis M Lindell, Susan B Morris, Maria P White, Lara E Kallal, Phillip K Lundy, Tarek Hamouda, James R Baker, Nicholas W Lukacs   +7 more
doaj   +1 more source

Pengaruh Pemberian Dosis Vaksin Avian Influenza Inaktif Pada Itik Jantan Terhadap Jumlah Sel Darah Putih Dan Titer Antibodi Yang Dihasilkan [PDF]

, 2016
The aim of research to knowing the effect of inactived AI (Avian Influenza) vaccine doses to white blood cells and titer of antibodies also to knowing the most well vaccine doses to white blood cells and titer of antibodies production, already ...
Santosa, P. E. (Purnama), Suharyati, S. (Sri), Yulistiya, E. (Eva)   +2 more
core  

An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs as demonstrated by a dose-titration [PDF]

, 2015
Citation: Collin, E. A., Anbalagan, S., Okda, F., Batman, R., Nelson, E., & Hause, B. M. (2015). An inactivated vaccine made from a U.S. field isolate of porcine epidemic disease virus is immunogenic in pigs as demonstrated by a dose-titration.
Anbalagan, S., Batman, R., Collin, E. A., Hause, Benjamin M., Nelson, E., Okda, F.   +5 more
core   +3 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Your Best Shot at Surviving the Flu Season [PDF]

, 2020
Millions of individuals become ill from the influenza virus every year. As an existing public health issue, it is important for patients to understand that the best way to combat the influenza virus is through prevention.
Liu, Isabella
core   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Effects of binary ethyleneimine and formaldehyde inactivation methods on foot-and-mouth disease virus vaccine immune responses and kinetics

Scientific Reports
Foot-and-mouth disease (FMD) is a highly contagious viral disease of livestock that has a significant economic impact on the country. The inactivated vaccine is the most widely used type of FMD vaccine, with the inactivation procedure being one of the ...
Wendyfraw Tsegaw Habtewold, Negesse Welde, Ambaye Kenubih, Yared Abate Getahun, Takele Abayneh, Belayneh Getachew, Wubet Woldemedhin, Yeneneh Tesfaye, Liyuwork Tesfaw, Yitbarek Getachew, Haileleul Negussie   +10 more
doaj   +1 more source

Pregnancy has a minimal impact on the acute transcriptional signature to vaccination. [PDF]

, 2020
Vaccination in pregnancy is an effective tool to protect both the mother and infant; vaccines against influenza, pertussis and tetanus are currently recommended.
Aerssens, A, Calvert, A, Cizmeci, D, Hake, D, Jones, CE, Kaufmann, SHE, Leroux-Roels, G, Maertzdorf, J, Maes, C, Tregoning, JS, Weiner, J   +10 more
core   +1 more source