Results 161 to 170 of about 132,203 (305)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Safety, immunogenicity, and efficacy of an mRNA COVID-19 vaccine (RQ3013) given as the fourth booster following three doses of inactivated vaccines: a double-blinded, randomised, controlled, phase 3b trial. [PDF]

EClinicalMedicine, 2023
Liu X, Sun Z, Wang Z, Chen J, Wu Q, Zheng Y, Yang X, Mo L, Yan X, Li W, Zou Y, Song H, Qian F, Lu J, Zhou H, Wang Y, Xiang Z, Yu H, Lin J, Yuan L, Zheng Y.   +20 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Immunogenicity profiling and distinct immune response in liver transplant recipients vaccinated with SARS-CoV-2 inactivated vaccines. [PDF]

Front Immunol, 2022
Duan B, Zhang G, Wang W, Yin J, Liu M, Zhang J, Chen D, Ouyang Y, Li G.   +8 more
europepmc   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Antiviral Inactivated Vaccines: Looking to the Past to Face the Future-A Narrative Review. [PDF]

Vaccines (Basel)
Guedes-da-Silva FH, Roncaglia-Pereira VA, Torres S, García MCE, Viana KF, Silva JL, Oliveira AC, Gomes AMO.   +7 more
europepmc   +1 more source

Virulence genes contributing to Aeromonas veronii pathogenicity in Nile tilapia (Oreochromis niloticus): approaching the development of live and inactivated vaccines. [PDF]

Aquac Int, 2023
Youssef HA, Ayoub HF, Soror EI, Matter AF.   +3 more
europepmc   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Genetic evolution of Akabane virus isolates and the protective efficacy of inactivated vaccines. [PDF]

Virol J
Wang P, Zhang M, Qi Y, Cao X, Ji W, Li X, Liu Z.   +6 more
europepmc   +1 more source

Comparative immunogenicity of mRNA and inactivated vaccines against COVID-19. [PDF]

Lancet Microbe, 2021
Lim WW, Mak L, Leung GM, Cowling BJ, Peiris M.   +4 more
europepmc   +1 more source