Results 61 to 70 of about 993,849 (289)

TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases [PDF]

open access: yes, 2019
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several ...
Amicone, Laura   +8 more
core   +1 more source

Movimento e inativação do metribuzin em materiais de dois solos, sob diferentes densidades aparentes Movement and inactivation of metribuzin in two soil materials with different bulk densities

open access: yesPlanta Daninha, 1980
Numa série de ensaios em laboratório e casa-de-vegetação, estudou-se a mobilidade e a inativação do herbicida metribuzin em materiais de um Latossolo e de um Podzólico representativos de duas regiões do Estado de Minas Gerais, em função de diferentes ...
L.E.F. Fontes   +2 more
doaj   +1 more source

Eugenol nanoemulsion inactivates Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7 on cantaloupes without affecting rind color

open access: yesFrontiers in Sustainable Food Systems, 2022
Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7 are the major foodborne pathogens that have been implicated in outbreaks related to consumption of contaminated cantaloupes.
Brindhalakshmi Balasubramanian   +7 more
doaj   +1 more source

A schistosome [beta] subunit remodels inactivation of a calcium channel _via_ an N-terminal polyacidic motif [PDF]

open access: yes, 2010
The beta subunit of high voltage-activated Ca (Cav) channels targets the pore forming [alpha]~1~ subunit to the plasma membrane and defines the biophysical phenotype of the Cav channel complex. Cav channel inactivation following activation and opening is
Robert M. Greenberg   +1 more
core   +1 more source

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

open access: yes, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M.   +3 more
core   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou   +9 more
wiley   +1 more source

Gain of function mutants: Ion channels and G protein-coupled receptors [PDF]

open access: yes, 2000
Many ion channels and receptors display striking phenotypes for gain-of-function mutations but milder phenotypes for null mutations. Gain of molecular function can have several mechanistic bases: selectivity changes, gating changes including constitutive
Karschin, Andreas, Lester, Henry A.
core   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

In-Vitro Inactivation of Sabin-Polioviruses for Development of Safe and Effective Polio Vaccine

open access: yesVaccines, 2020
After years of global collaboration; we are steps away from a polio-free world. However, the currently conventional inactivated polio vaccine (cIPV) is suboptimal for the post eradication era.
Asmaa A. Abd-Elghaffar   +3 more
doaj   +1 more source

Aerosol Survival, Disinfection and Formalin Inactivation of Nipah Virus

open access: yesViruses, 2022
Nipah virus is a relatively newly discovered emerging virus on the WHO list of priority pathogens which has the potential to cause outbreaks with high fatality rates.
Sophie J. Smither   +4 more
doaj   +1 more source

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