Results 101 to 110 of about 369,106 (309)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Gross motor development, physical activity and anthropometry of Grade 1’s in a South African school

open access: yesSouth African Journal of Childhood Education
Background: Gross motor difficulties can limit physical activity (PA) participation, contributing to unhealthy body composition. Aim: This study profiled Grade 1 learners’ gross motor development, PA and anthropometry and explored relationships between ...
Monique de Milander   +3 more
doaj   +1 more source

Shortchanging America's Health 2008: A State-by-State Look at How Federal Public Health Dollars Are Spent [PDF]

open access: yes, 2008
Examines public health indicators in each state, in combination with federal and state funding for programs to promote health. Includes state rankings by funding per capita, percentage of population who are uninsured, disease rates, and other ...
Jeffrey Levi   +2 more
core  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Individual and collective learned helplessness syndrome: causes, signs, and ways to overcome

open access: yesClío
This study addresses the growing relevance of learned helplessness in the face of global socio-cultural changes that demand independence, responsibility, and competence.
Olga Ishchuk   +3 more
doaj   +1 more source

ASSESSING THE SELF-ESTEEM OF SEDENTARY AND PHYSICALLY ACTIVE STUDENTS [PDF]

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2019
The present research aimed to evaluate the self-esteem of physically active female students and sedentary female students. By doing this, I aim to establish to what extent physical exercise contributes to improving self-esteem and the degree of ...
Andreea – Gabriela Lazăr
doaj  

Educational mismatch of disadvantaged groups in the labour [PDF]

open access: yes
In this article, we analyze the job-matching quality of people with disabilities. We do not find evidence of a higher importance of over- education in this group in comparison to the rest of the population. The main results are the following: people with
Maite Blázquez, Miguel Angle Malo
core  

2014 Rankings: Key Findings Report [PDF]

open access: yes, 2014
The County Health Rankings & Roadmaps program helps communities identify and implement solutions that make it easier for people to be healthy in their schools, workplaces, and neighborhoods.
Amanda Jovaag   +3 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Women post-recession: moving towards insecurity [PDF]

open access: yes, 2015
After the recession, the rise in casual and precarious contracts is entrenching gender inequality in the ...
Ross, Susanne Louise, Thomson, Emily
core   +1 more source

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