Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini +7 more
wiley +1 more source
Assessment of inappropriate antibiotic use in pediatric patients: Point-prevalence study. [PDF]
Turk Pediatri Ars, 2018 Ergül AB +3 more
europepmc +1 more source
What Matters Most: A Case of Pemphigus Vulgaris in a Nonagenarian Physician
Journal of the American Geriatrics Society, EarlyView.
Svetlana Bagdasarov +6 more
wiley +1 more source
A Population Pharmacokinetic Model of Gentamicin in Hospitalized Neonatal Foals
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Information on safe and effective gentamicin dosing in foals is limited. This study aimed to provide guidance regarding optimal dosing regimens by means of a population pharmacokinetic (popPK) model. Gentamicin plasma concentration of 290 samples from 72 hospitalized foals (≤ 14 days old), treated with intravenous (IV) gentamicin, was measured
Astrid J. van den Brom‐Spierenburg +12 more
wiley +1 more source
The Association between Changes in External Environment Caused by Migration and Inappropriate Antibiotic Use Behaviors among Chinese University Students: A Cross-Sectional Study. [PDF]
Antibiotics (Basel), 2019 Lu J +5 more
europepmc +1 more source
First‐Line Provider Patterns and Primary Care Intervals in Oral–Oropharyngeal Cancer
Oral Diseases, EarlyView.ABSTRACT Objectives Early detection improves survival of oral and oropharyngeal cancer (OPC), yet diagnostic delays remain common. Primary care intervals (PCIs) contribute to this delay. This study examined first‐line health care providers (HCPs) consulted by undiagnosed OPC patients, reasons for choice and PCI lengths.
Agnieszka M. Frydrych +5 more
wiley +1 more source
A multifaceted approach to decrease inappropriate antibiotic use in a pediatric outpatient clinic. [PDF]
Ann Thorac Med, 2017 Al-Tawfiq JA, Alawami AH.
europepmc +1 more source
First Experience With Extravascular Implantable Cardioverter‐Defibrillator Under Deep Sedation
Pacing and Clinical Electrophysiology, EarlyView.ABSTRACT Background The Extravascular Implantable Cardioverter‐Defibrillator (EV‐ICD) utilizes a substernal lead to provide defibrillation and anti‐tachycardia pacing (ATP) while avoiding transvenous complications. General anesthesia (GA) was applied for implantation procedures in the EV‐ICD pivotal trial and is currently recommended by the ...
Nibras Soubh +9 more
wiley +1 more source
Periodontology 2000, EarlyView.Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley +1 more source