Results 101 to 110 of about 113,820 (337)
Inborn Errors of Metabolism: The Croonian Lectures Delivered Before the Royal College of Physicians of London, in June, 1908. [PDF]
, 1909 openalex +1 more source
An Amygdala‐hippocampus Circuit for Endocannabinoid Modulation of Anxiety Avoidance
Advanced Science, EarlyView.This study employs three synapse‐specific endocannabinoids (eCB) probes to monitor dynamic eCB release, activate CB1Rs and knockdown 2‐AG biosynthesis enzymes in glutamatergic anterior basolateral amygdala ‐ ventral hippocampus (aBLA–vHPC) circuit. At aBLA–vHPC circuits, activation of CB1Rs reduce anxiety avoidance, and knockdown of eCB biosynthesis ...
Bao Xue +9 more
wiley +1 more source
Some Philosophical Remarks on Educating Genuine Leaders [PDF]
, 2012 The author intends to make an appeal for paying closer attention to human nature in educating genuine leaders. His philosophical approach embraces following topics: (1) whether leaders are born with talents and traits that allow, or even cause, them to ...
Tarasiewicz, Pawel
core
Advanced Science, EarlyView.Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo +11 more
wiley +1 more source
The Integrity of Thinking [PDF]
, 2018 When we look at our political landscape today, I wonder where has our integrity gone? Teachers want to know how to explain (if that’s the right word) the language and behavior of the current American president to children in their ...
Tillmanns, Maria daVenza
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Dysmorphology of inborn errors of metabolism [PDF]
Molecular Cytogenetics, 2014 As we discover the molecular mechanism of disorders, eventually all dysmorphic syndromes will ultimately be considered biochemical defects. An overview on the recognition and classification of dysmorphic features will be provided. Categories of inborn errors of metabolism associated with dysmorphic manifestations will be discussed. For e.g.
openaire +3 more sources
BRD4 Signaling Maintains the Differentiated State of β Cells
Advanced Science, EarlyView.The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu +22 more
wiley +1 more source
Molecular Genetics and Metabolism Reports, 2020 Short-chain enoyl-CoA hydratase (ECHS1) is a mitochondrial beta-oxidation enzyme involved in the metabolism of acyl-CoA fatty acid esters, as well as in valine metabolism.
S. Pajares +13 more
doaj
Newborn screening using tandem mass spectrometry: A systematic review [PDF]
Objectives: To evaluate the evidence for the clinical effectiveness of neonatal screening for phenylketonuria (PKU) and medium-chain acyl-coA dehydrogenase (MCAD) deficiency using tandem mass spectrometry (tandem MS).
Beverley, C. +4 more
core
ARE LEFT HANDED SURGEONS LEFT OUT? [PDF]
, 2012 Being a left-handed surgeon, more specifically a left-handed ENT surgeon, presents a unique pattern of difficulties.This article is an overview of left-handedness and a personal account of the specific difficulties a left-handed ENT surgeon faces.
Kothandaraman, SriKamkshi +1 more
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