Results 231 to 240 of about 45,424 (315)

Parental Decision‐Making Following a Prenatal Diagnosis of Turner Syndrome: A Systematic Review

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT This systematic review investigates factors influencing parental decision‐making following a prenatal diagnosis (PND) of Turner syndrome (TS), aiming to enhance the foundation for tailored and supportive genetic counseling. A comprehensive literature search was conducted in the medical databases PubMed, Embase, and CINAHL.
Inger Lily Hjuler Dorf, Stina Lou, Anne Skakkebæk   +2 more
wiley   +1 more source

Monitoring of immunoglobulin treatment compliance of patients with an inborn error of immunity during the pandemic period. [PDF]

BMC Immunol
Karali Y, Karali Z, Cekic S, Cakir I, Kilic SS.   +4 more
europepmc   +1 more source

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Centralisation of extremely preterm births and decreased early postnatal mortality in Sweden, 2004-2007 versus 2014-2016. [PDF]

Acta Paediatr
Gadsbøll C, Björklund LJ, Norman M, Abrahamsson T, Domellöf M, Elfvin A, Farooqi A, Hellström-Westas L, Håkansson S, Källén K, Normann E, Serenius F, Sävman K, Um-Bergström P, Ådén U, Ley D.   +15 more
europepmc   +1 more source

Metabolic engineering as therapy for inborn errors of metabolism – development of mice with phenylalanine hydroxylase expression in muscle

, 1998
CO Harding, Krzysztof Wild, David Chang, Albee Messing, JA Wolff   +4 more
openalex   +1 more source

System genetic analysis of intestinal cancer and periodontitis development as influenced by aging and diabesity using Collaborative Cross mice

Animal Models and Experimental Medicine, EarlyView.
It is increasingly recognized that young, chow‐fed inbred mice poorly model the complexity of human carcinogenesis in multiple respects. In humans, age and adiposity are the major risk factors for the majority of malignancies. Although the development of genetically engineered mouse models (GEMM) of cancer has recapitulated many aspects of human cancer,
Iqbal M. Lone, Osayd Zohud, Kareem Midlej, Charles Brenner, Fuad A. Iraqi   +4 more
wiley   +1 more source

Editorial: Reviews in pediatric primary immunodeficiencies. [PDF]

Front Pediatr
Kilic SS.
europepmc   +1 more source

Animal models of human herpesvirus infection

Animal Models and Experimental Medicine, EarlyView.
Human herpesvirus can infect humans and other vertebrates, primarily targeting the skin, mucous membranes, and neural tissues, thereby significantly impacting the health of both humans and animals. Animal models are crucial for studying virus pathogenesis, vaccine development, and drug testing.
Ziqing Jia, Dong Zhang, Lin Zhu, Jing Xue   +3 more
wiley   +1 more source

Lymphoproliferation and hyper-IgM as the first manifestation of activated phosphoinositide 3-kinase δ syndrome: A case report. [PDF]

Biomedica
Fernandes-Pineda M, Zea-Vera AF.
europepmc   +1 more source

A new CRISPR‐mediated Apc knockout allele leads to pyloric gland adenoma‐like gastric polyps in mice with C57BL/6;FVB/N mixed background

Animal Models and Experimental Medicine, EarlyView.
The exon 16 of the mouse Apc gene was targeted with CRISPR/Cas9 system and a novel Apc knockout mouse model was generated by creating a frameshift mutation at codon 750 (ApcΔ750). The polyp number, polyp distribution and the overall survival of mice carrying the ApcΔ750 allele significantly differs between the F8‐FVB‐ApcΔ750 and F4‐B6;FVB‐ApcΔ750 mouse
Sarp Uzun, Özge Özcan, Ayşenur Gök, Aynur Işık, Sinem Bakır, Ayşen Günel‐Özcan, İlyas Onbaşılar, Aytekin Akyol   +7 more
wiley   +1 more source