Results 261 to 270 of about 15,747 (332)

Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases

BioEssays, Volume 47, Issue 10, October 2025.
The Role of Ribosome Recycling in Human Diseases This diagram highlights how disruptions in ribosome translation and recycling can negatively impact cellular and organismal health. Usually, these processes operate efficiently to maintain cellular protein homeostasis.
Foozhan Tahmasebinia, Zhihao Wu
wiley   +1 more source

Gender‐Based Differences in Gut Microbiota Composition in Response to Anxiety and Stress in Shooting and Archery Athletes

Brain and Behavior, Volume 15, Issue 10, October 2025.
The study found that anxious athletes exhibited higher relative abundance of Firmicutes and lower levels of Actinobacteria. Predictive analyses revealed that male athletes showed increased endoplasmic reticulum protein processing, while anxious females demonstrated reduced base excision repair functions.
Yuhuan Wei, Shaoye Huo, Ruyue Liang, Yuan Cui, Lihong Wang, Yunhua Zhao, Chao Zhao, Chunhai Shao   +7 more
wiley   +1 more source

Enhancing the Prediction of Inborn Errors of Immunity: Integrating Jeffrey Modell Foundation Criteria with Clinical Variables Using Machine Learning. [PDF]

Children (Basel)
Yorulmaz A, Şahin A, Sonmez G, Eldeniz FC, Gül Y, Karaselek MA, Güler ŞN, Keleş S, Reisli İ.   +8 more
europepmc   +1 more source

Early Postnatal Infection With Human Cytomegalovirus Has Long‐Term Consequences on Brain Structure of Former Preterm Born Children

Brain and Behavior, Volume 15, Issue 10, October 2025.
Cortical surface analyses of former preterm‐born children with (PT hCMV+) and without (PT hCMV−) early postnatal human Cytomegalovirus (hCMV) infection at ∼13 years of age. Note the strong effect of prematurity when compared to full‐term‐born children (FT, top), but the independent and even more widespread effect of HCMV infection (bottom).
Meike Müller, Karen Lidzba, Christian Gaser, Till‐Karsten Hauser, Rangmar Goelz, Klaus Hamprecht, Marko Wilke   +6 more
wiley   +1 more source

IEIVariantFilter: a bioinformatics tool to speed up genetic diagnosis of inborn errors of immunity patients. [PDF]

NAR Genom Bioinform
Pereda J, Espinosa R, García-Solís B, Guerra-Galán T, Van-Den-Rym A, Kars ME, Mena R, Galán V, de Andrés-Martín A, Rodríguez-Gallego C, López-Lera A, Corvillo F, Pérez-Martínez A, López-Collazo E, Sánchez-Ramón S, Martínez-Barricarte R, Quintana-Murci L, Lorenzo-Salazar JM, Itan Y, Flores C, Pérez-de-Diego R.   +20 more
europepmc   +1 more source

Challenges in the Immune System: Mesoscale and Mesoregime Complexity

Cancer Innovation, Volume 4, Issue 5, October 2025.
The immune system is multilevel in nature, with each level showing multiscale properties, and the complexity emerging always at mesoscales in mesoregimes governed by the compromise in competition between at least two dominant mechanisms at each level.
Ying Ren, Ai‐Guo Wu, Yu Shi, Yi‐Fang Ping, Jing‐Hai Li, Xiu‐Wu Bian   +5 more
wiley   +1 more source

Causes of Mortality in Patients with Inborn Errors of Immunity: An 18-year retrospective cohort study. [PDF]

Sultan Qaboos Univ Med J
Al-Tamemi S, Jabri MA, Abdalla E, Al-Busaidi I, Al-Zeedy K, Al Yazidi L.   +5 more
europepmc   +1 more source

Humanized Mouse Models for Type 1 Diabetes

Current Protocols, Volume 5, Issue 10, October 2025.
Abstract T cell–mediated autoimmune type 1 diabetes (T1D) is under complex polygenic control in both humans and the NOD mouse model. However, in both species, particular major histocompatibility complex (MHC; designated HLA in humans) haplotypes provide the primary T1D risk factor. Both MHC/HLA class I and II variants interactively contribute to T1D by
David V. Serreze, Marissa Tousey‐Pfarrer, Jeremy J. Racine   +2 more
wiley   +1 more source

Abundant Yet Aberrant T Helper Cell Responses to Candida albicans Underlie Mucosal Candidiasis in Humans and Mice

European Journal of Immunology, Volume 55, Issue 10, October 2025.
Th17 cells confer protection against Candida albicans infection. In patients with STAT1 gain‐of‐function (GOF) mutations and chronic mucocutaneous candidiasis (CMC), Candida‐specific Th cell responses are numerically preserved but skewed toward Th1 and Th2.
Camilla Basso, Corinne De Gregorio, Roberta Marzi, Florian Kirchner, Gabor Gyülveszi, Mélanie Migaud, Sinu Paul, Alessandro Sette, Antonio Lanzavecchia, Salomé LeibundGut‐Landmann, Jean‐Laurent Casanova, Anne Puel, Simone Becattini, Federica Sallusto   +13 more
wiley   +1 more source

The Prevalence of Toxoplasmosis Antibodies Among Pregnant Women Attending Antenatal Care Services in Urban and Rural Health Facilities in Three Regions of Burkina Faso: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Congenital toxoplasmosis can cause severe diseases to the fetus and newborns or abortion, and is associated with significant morbidity and mortality. In Burkina Faso, while seroprevalence data for toxoplasmosis are available for urban areas, such data are scarce for rural areas.
Achille Sindimbasba Nikièma, Armel Moumouni Sanou, Mamadou Ouattara, Barnabé Relwendé Yaméogo, Ad Bafa Ibrahim Ouattara, Mariam Seynou, Djara Konaté, Nina Geneviève Mathuola Ouattara, Dieudonné Ilboudo, Ina Marie Angèle Traoré, Henri Gauthier Ouédraogo   +10 more
wiley   +1 more source