Results 271 to 280 of about 15,747 (332)

Immunoinformatics‐Based Multi‐Epitope Vaccine Design Against P. falciparum‐Causing Malaria: A Computational Approach

open access: yesHealth Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aim Malaria is an infectious disease that affects people in Africa, and other parts of the world by the millions. Despite the effectiveness of artemisinin‐based combination therapies against the disease, current findings on possible Plasmodium resistance to artemisinin warrants an exploration of new treatment options. This study
Amma Aboagyewa Larbi   +6 more
wiley   +1 more source

Preterm Birth Conditions Alter Muscle Stem Cells and Their Niche, Causing Lasting Impairments in Muscle Regeneration and Function

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Preterm birth‐related conditions affect the development of multiple organs, such as the heart, the lungs and the brain, leading to long‐term alterations in their function and a higher risk of comorbidities. Emerging evidence also indicates that the skeletal muscles are affected. We aimed to understand the mechanisms underlying these
Alyson Deprez   +9 more
wiley   +1 more source

Prevalence of Ophthalmological Manifestations in Patients with Inborn Errors of Immunity: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Clin Immunol
Zárate-Pinzón L   +9 more
europepmc   +1 more source

Genetic landscape of Romanian children with inborn errors of immunity via gene panels, exome, and genome sequencing. [PDF]

open access: yesSci Rep
Pantea CL   +5 more
europepmc   +1 more source

Amniotic Fluid Extracellular Vesicle Properties Evolve With Gestational Age and Reflect Fetal Development

open access: yesJournal of Extracellular Biology, Volume 4, Issue 10, October 2025.
This figure summarises the study's main findings, including the shift in the predominant EV subtype, the different organs and biofluids represented by the enriched proteins at each gestational age, and the main biological pathways. ABSTRACT Amniotic fluid (AF) is a valuable source of extracellular vesicles (EVs) derived from the fetoplacental unit ...
Ishara Atukorala   +9 more
wiley   +1 more source

The Association of RNase L, Cytokines, and Chemokines With Severity of Multisystem Inflammatory Syndrome in Children

open access: yesJournal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT The 2′,5′‐oligoadenylate synthetase (OAS)‐ribonuclease L (RNase L) system, induced by type I interferons, defends against RNA viruses. Inborn errors in this pathway may trigger inflammatory cytokines, contributing to SARS‐CoV‐2‐related multisystem inflammatory syndrome in children (MIS‐C).
Ting‐Yu Yen   +13 more
wiley   +1 more source

Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Its Implications for Prophylactic and Therapeutic Pharmaceuticals

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Respiratory syncytial virus (RSV) causes substantial global morbidity, particularly in infants and elderly populations. This review summarizes key viral pathogenesis mechanisms and highlights recent advances in both prophylactic (vaccines, antibodies) and therapeutic (antiviral agents) strategies against RSV.
Xiaowen Liang   +7 more
wiley   +1 more source

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