Results 21 to 30 of about 2,284,318 (330)

Behavioral profiles of three C57BL/6 substrains

Frontiers in Behavioral Neuroscience, 2010
C57BL/6 inbred strains of mice are widely used in knockout and transgenic research. To evaluate the loss-of-function and gain-of-function effects of the gene of interest, animal behaviors are often examined.
Naoki Matsuo, Naoki Matsuo, Keizo Takao, Keizo Takao, Keizo Takao, Keizo Takao, Kazuo Nakanishi, Nobuyuki Yamasaki, Nobuyuki Yamasaki, Koichi Tanda, Koichi Tanda, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa   +15 more
doaj   +1 more source

Individual identification of inbred medaka based on characteristic melanophore spot patterns on the head

Scientific Reports, 2023
With disease progression, individual differences appear, even in an animal disease model with genetic homogeneity. Therefore, non-invasive long term observation and individual identification is desirable for late-onset diseases.
Hajime Morizumi, Naozo Sugimoto, Tomohiro Ueno   +2 more
doaj   +1 more source

Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice

Journal of Bone and Mineral Research, 2008
Inbred strain‐specific differences in mice exist in bone cross‐sectional geometry, mechanical properties, and indices of bone formation. Inbred strain‐specific responses to external stimuli also exist, but the role of background strain in response to ...
Joseph M. Wallace, K. Golcuk, M. Morris, D. Kohn   +3 more
semanticscholar   +1 more source

Identification of collaborative cross mouse strains permissive to Salmonella enterica serovar Typhi infection

Scientific Reports, 2023
Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli, Sudeep Kothari, Matthew P. Cravens, Justin A. Walker, Darren T. Dougharty, Gregory S. Dickinson, Louis A. Gatto, Andreas J. Bäumler, Tamding Wangdi, Darla R. Miller, Fernando Pardo-Manuel de Villena, Linda D. Siracusa   +11 more
doaj   +1 more source

Distribution of endogenous gammaretroviruses and variants of the Fv1 restriction gene in individual mouse strains and strain subgroups.

PLoS ONE, 2019
Inbred laboratory mouse strains carry endogenous retroviruses (ERVs) classed as ecotropic, xenotropic or polytropic mouse leukemia viruses (E-, X- or P-MLVs).
Matthew Skorski, Devinka Bamunusinghe, Qingping Liu, Esther Shaffer, Christine A Kozak   +4 more
doaj   +1 more source

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

Laboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim, Jun Gyo Suh   +5 more
doaj   +1 more source

Differences in Immune Defense Evasion of Selected Inbred Lines of Heterorhabditis Bacteriophora in Two White Grub Species

Insects, 2012
We determined virulence of seven Heterorhabditis bacteriophora strain GPS11 inbred lines possessing superior infective juvenile longevity, and heat and ultra violet radiation tolerance against white grubs Popillia japonica and Cyclocephala borealis. At 1
Ganpati B. Jagdale, Parwinder S. Grewal, Marcio Voss, Ruisheng An   +3 more
doaj   +1 more source

Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice

Metabolites, 2022
Genetics play an important role in the development of metabolic diseases. However, the relative influence of genetic variation on metabolism is not well defined, particularly in tissues, where metabolic dysfunction that leads to disease occurs.
Ann E. Wells, William T. Barrington, Stephen Dearth, Nikhil Milind, Gregory W. Carter, David W. Threadgill, Shawn R. Campagna, Brynn H. Voy   +7 more
doaj   +1 more source

Quantitative trait loci determining weight reduction of testes and pituitary by diethylstilbesterol in LEXF and FXLE recombinant inbred strain rats.

Experimental animals, 2006
Increasing exposure to environmental endocrine disruptor, xeno-estrogen, is a serious hazard to male reproductive activity. To explore possible genetic control in susceptibility to xeno-estrogen, the weight reduction of testes induced by the continuous ...
M. Tachibana, Ling‐min Lu, H. Hiai, A. Tamura, Y. Matsushima, H. Shisa   +5 more
semanticscholar   +1 more source

Genomic Analysis Reveals Specific Patterns of Homozygosity and Heterozygosity in Inbred Pigs

Animals, 2019
The inbred strain of miniature pig is an ideal model for biomedical research due to its high level of homozygosity. In this study, we investigated genetic diversity, relatedness, homozygosity, and heterozygosity using the Porcine SNP60K BeadChip in both ...
Ligang Wang, Yulian Mu, Linyang Xu, Kui Li, Jianlin Han, Tianwen Wu, Lan Liu, Qian Gao, Ying Xia, Guanyu Hou, Shulin Yang, Xiaohong He, George E. Liu, Shutang Feng   +13 more
doaj   +1 more source