Results 21 to 30 of about 2,378,055 (316)

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source

Choosing mates based on the diet of your ancestors: replication of non-genetic assortative mating in Drosophila melanogaster [PDF]

PeerJ, 2015
Assortative mating has been a focus of considerable research because of its potential to influence biodiversity at many scales. Sharon et al. (2010) discovered that an inbred strain of Drosophila melanogaster mated assortatively based on the diet of ...
Michael A. Najarro, Matt Sumethasorn, Alexandra Lamoureux, Thomas L. Turner   +3 more
doaj   +2 more sources

Effects of inbreeding and genetic modification on Aedes aegypti larval competition and adult energy reserves

Parasites & Vectors, 2010
Background Genetic modification of mosquitoes offers a promising strategy for the prevention and control of mosquito-borne diseases. For such a strategy to be effective, it is critically important that engineered strains are competitive enough to serve ...
Kormaksson Matthias, Koenraadt Constantianus JM, Harrington Laura C   +2 more
doaj   +1 more source

Micromolar Valproic Acid Doses Preserve Survival and Induce Molecular Alterations in Neurodevelopmental Genes in Two Strains of Zebrafish Larvae

Biomolecules, 2020
Autism spectrum disorders (ASDs) comprise a genetically heterogeneous group of conditions characterized by a multifaceted range of impairments and multifactorial etiology.
Andrea Messina, Alessandra Boiti, Valeria Anna Sovrano, Paola Sgadò   +3 more
doaj   +1 more source

Individual identification of inbred medaka based on characteristic melanophore spot patterns on the head

Scientific Reports, 2023
With disease progression, individual differences appear, even in an animal disease model with genetic homogeneity. Therefore, non-invasive long term observation and individual identification is desirable for late-onset diseases.
Hajime Morizumi, Naozo Sugimoto, Tomohiro Ueno   +2 more
doaj   +1 more source

Behavioral profiles of three C57BL/6 substrains

Frontiers in Behavioral Neuroscience, 2010
C57BL/6 inbred strains of mice are widely used in knockout and transgenic research. To evaluate the loss-of-function and gain-of-function effects of the gene of interest, animal behaviors are often examined.
Naoki Matsuo, Naoki Matsuo, Keizo Takao, Keizo Takao, Keizo Takao, Keizo Takao, Kazuo Nakanishi, Nobuyuki Yamasaki, Nobuyuki Yamasaki, Koichi Tanda, Koichi Tanda, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa, Tsuyoshi Miyakawa   +15 more
doaj   +1 more source

Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice

Journal of Bone and Mineral Research, 2008
Inbred strain‐specific differences in mice exist in bone cross‐sectional geometry, mechanical properties, and indices of bone formation. Inbred strain‐specific responses to external stimuli also exist, but the role of background strain in response to ...
Joseph M. Wallace, K. Golcuk, M. Morris, D. Kohn   +3 more
semanticscholar   +1 more source

Distribution of endogenous gammaretroviruses and variants of the Fv1 restriction gene in individual mouse strains and strain subgroups.

PLoS ONE, 2019
Inbred laboratory mouse strains carry endogenous retroviruses (ERVs) classed as ecotropic, xenotropic or polytropic mouse leukemia viruses (E-, X- or P-MLVs).
Matthew Skorski, Devinka Bamunusinghe, Qingping Liu, Esther Shaffer, Christine A Kozak   +4 more
doaj   +1 more source

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

Laboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim, Jun Gyo Suh   +5 more
doaj   +1 more source

Identification of collaborative cross mouse strains permissive to Salmonella enterica serovar Typhi infection

Scientific Reports, 2023
Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli, Sudeep Kothari, Matthew P. Cravens, Justin A. Walker, Darren T. Dougharty, Gregory S. Dickinson, Louis A. Gatto, Andreas J. Bäumler, Tamding Wangdi, Darla R. Miller, Fernando Pardo-Manuel de Villena, Linda D. Siracusa   +11 more
doaj   +1 more source