Results 31 to 40 of about 206,991 (267)

Distribution of endogenous gammaretroviruses and variants of the Fv1 restriction gene in individual mouse strains and strain subgroups.

PLoS ONE, 2019
Inbred laboratory mouse strains carry endogenous retroviruses (ERVs) classed as ecotropic, xenotropic or polytropic mouse leukemia viruses (E-, X- or P-MLVs).
Matthew Skorski, Devinka Bamunusinghe, Qingping Liu, Esther Shaffer, Christine A Kozak   +4 more
doaj   +1 more source

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour, A Reverter, A Subramanian, AJ Butte, BA Taylor, BE Stranger, BH Voy, C Wu, Chris J. Cotsapas, CJ Cotsapas, D Gatti, D Vlieghe, David J. Nott, E Petretto, EJ Chesler, EJ Chesler, EJ Foss, Eva K. F. Chan, G Gibson, G Passador-Gurgel, HH Goring, I Hovatta, I Lönnstedt, J Brumm, JC Gower, Jeremy N. Pulvers, JJ Keurentjes, JJ Nadler, KA Frazer, L Bystrykh, M Bansal, M Mehrabian, M Wirth, MA West, Mark J. Cowley, MC Frith, Michael Y. Liu, MP Keller, MT Pletcher, MV Rockman, N Hubner, NN Batada, Oscar J. Luo, P Blache, Peter F. R. Little, R Ihaka, R Sandberg, RB Brem, RB Williams, RC Gentleman, RM Kuhn, Rohan B. H. Williams, S Biswas, TC Freeman, TM Fruchterman, V Emilsson, X Yang, Y Chen, Y Fukuoka   +58 more
core   +4 more sources

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

Laboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam, Yoo Yeon Kim, Boyoung Kim, Won Kee Yoon, Hyoung-Chin Kim, Jun Gyo Suh   +5 more
doaj   +1 more source

Identification of collaborative cross mouse strains permissive to Salmonella enterica serovar Typhi infection

Scientific Reports, 2023
Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli, Sudeep Kothari, Matthew P. Cravens, Justin A. Walker, Darren T. Dougharty, Gregory S. Dickinson, Louis A. Gatto, Andreas J. Bäumler, Tamding Wangdi, Darla R. Miller, Fernando Pardo-Manuel de Villena, Linda D. Siracusa   +11 more
doaj   +1 more source

Differences in Immune Defense Evasion of Selected Inbred Lines of Heterorhabditis Bacteriophora in Two White Grub Species

Insects, 2012
We determined virulence of seven Heterorhabditis bacteriophora strain GPS11 inbred lines possessing superior infective juvenile longevity, and heat and ultra violet radiation tolerance against white grubs Popillia japonica and Cyclocephala borealis. At 1
Ganpati B. Jagdale, Parwinder S. Grewal, Marcio Voss, Ruisheng An   +3 more
doaj   +1 more source

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains [PDF]

, 2012
BACKGROUND: miRNAs are short single-stranded non-coding RNAs involved in post-transcriptional gene regulation that play a major role in normal biological functions and diseases. Little is currently known about how expression of miRNAs is regulated.
Chesler, E., Fernandes, C., Grimm, C., Lehrach, H., Liu, L., Nietfeld, W., Parsons, M., Paya-Cano, J., Philip, V., Schalkwyk, L.   +9 more
core   +3 more sources

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]

, 2009
Peer reviewedPublisher ...
Blizard, David A, Koide, Tsuyoshi, Kuriki, Satoshi, Lionikas, Arimantas, Nishi, Akinori, Sakaguchi, Takayuki, Umemori, Juzoh   +6 more
core   +3 more sources

Genomic Analysis Reveals Specific Patterns of Homozygosity and Heterozygosity in Inbred Pigs

Animals, 2019
The inbred strain of miniature pig is an ideal model for biomedical research due to its high level of homozygosity. In this study, we investigated genetic diversity, relatedness, homozygosity, and heterozygosity using the Porcine SNP60K BeadChip in both ...
Ligang Wang, Yulian Mu, Linyang Xu, Kui Li, Jianlin Han, Tianwen Wu, Lan Liu, Qian Gao, Ying Xia, Guanyu Hou, Shulin Yang, Xiaohong He, George E. Liu, Shutang Feng   +13 more
doaj   +1 more source

SNPs, short tandem repeats, and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrains

Cell Genomics, 2022
Summary: Mouse substrains are an invaluable model for understanding disease. We compared C57BL/6J, which is the most commonly used inbred mouse strain, with eight C57BL/6 and five C57BL/10 closely related inbred substrains.
Milad Mortazavi, Yangsu Ren, Shubham Saini, Danny Antaki, Celine L. St. Pierre, April Williams, Abhishek Sohni, Miles F. Wilkinson, Melissa Gymrek, Jonathan Sebat, Abraham A. Palmer   +10 more
doaj   +1 more source

Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice

Metabolites, 2022
Genetics play an important role in the development of metabolic diseases. However, the relative influence of genetic variation on metabolism is not well defined, particularly in tissues, where metabolic dysfunction that leads to disease occurs.
Ann E. Wells, William T. Barrington, Stephen Dearth, Nikhil Milind, Gregory W. Carter, David W. Threadgill, Shawn R. Campagna, Brynn H. Voy   +7 more
doaj   +1 more source