Results 71 to 80 of about 206,991 (267)

Immunomodulatory effect of cimetidine on the proliferative responses of splenocytes from T. cruzi-infected rats Efeito imunomodulatório da cimetidina sobre a resposta blastogênica de esplenócitos de ratos infectados por T. cruzi

Revista do Instituto de Medicina Tropical de São Paulo, 1991
The immunomodulatory effect of cimetidine (CIM), a histamine type-2 receptor antagonist, was evaluated in respect to the blastogenic response to Con A of Wistar Furth (WF) rats infected by the Y strain of Trypanosoma cruzi (T. cruzi).
M.N. Sato, E.H. Yamashiro-Kanashiro, M.M. Tanji, R. Kaneno, R.Y. Iqueoka, A.J.S. Duarte   +5 more
doaj   +1 more source

A program of corn improvement [PDF]

, 1924
Cover ...
Woodworth, Clyde Melvin
core  

Innate immune basis for rift valley fever susceptibility in mouse models [PDF]

, 2017
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre, Flamand, Marie, Godon, Ophélie, Jouvion, Grégory, Lathan, Rashida, Malissen, Marie, Panthier, Jean-Jacques, Simon-Chazottes, Dominique   +7 more
core   +2 more sources

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Genetic basis of voluntary water consumption in two divergently selected strains of inbred mice

Veterinary Medicine and Science, 2019
Background Inbred mouse strains with normal renal function show a substantial difference in daily water consumption across strains. This study uses two strains of inbred mice C57BR/CDJ (BR), which are high consumers, and C57BL/10J (BL), which are low ...
Maria Haag, Kevin Wells, William Lamberson   +2 more
doaj   +1 more source

High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains

Scientific Reports, 2021
Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses.
Sam-Moon Kim, Chelsea A. Vadnie, Vivek M. Philip, Leona H. Gagnon, Kodavali V. Chowdari, Elissa J. Chesler, Colleen A. McClung, Ryan W. Logan   +7 more
doaj   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Microsatellite Marker Analysis for Laboratory Mice Profiling

Advanced Biomedical Research, 2019
Background: The key point in the production procedure of inbred animals is checking the genetic purity. Skin grafting and coat color test are used traditionally to prove genetic purity, but they have some disadvantages.
Reza Ahangari Cohan, Davoud Nouri Inanlou, Mohammad Hasan Samiee Aref, Sirous Zeinali, Ramin Farhoudi   +4 more
doaj   +1 more source

Dysfunctional play and dopamine physiology in the Fischer 344 rat

, 2011
Juvenile Fischer 344 rats are known to be less playful than other inbred strains, although the neurobiological substrate(s) responsible for this phenotype is uncertain.
Akopian, Akopian, Akopian, Alcaro, Alessandri, Almeida, Baldwin, Bamford, Basar, Beatty, Beatty, Bell, Berridge, Breier, Broderick, Burgdorf, Burgdorf, Burghardt, Burghardt, Burghardt, Cadoni, Cadoni, Calabresi, Chambers, Cheng, Cordier, Crawford, Crawley, Cynthia A. Crawford, Davis, Depoortere, Fagen, Feifel, Field, Fleckenstein, Gainetdinov, Garnik Akopian, Garris, Geyer, Glowa, Gomez-Serrano, Gonon, Gordon, Guitart, Gulley, Guo, Gurden, Hariri, Harris, Helmeste, Huang, Huang, Hubbard, Humphries, Ikemoto, John P. Walsh, Kerr, Knutson, Kolomiets, Kosten, Leblois, Leipold, McGraw La, Meaney, Miles, Niesink, Panksepp, Panksepp, Panksepp, Panksepp, Panksepp, Patel, Patel, Pellegrini, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Pellis, Petzinger, Pliszka, Reif, Robinson, Romeo, Sagvolden, Schulte, Sills, Siviy, Siviy, Siviy, Siviy, Siviy, Siviy, Skuse, Smith, Smith, Spear, Spinka, Stamford, Stephen M. Siviy, Stohr, Sulzer, Surmeier, Swerdlow, Swerdlow, Swerdlow, Tang, Terranova, Trezza, Trezza, Trezza, Trezza, Tripp, Van den Berg, Vanderschuren, Vanderschuren, Vanderschuren, Varty, Villar, Volkow, Voorn, Walker, Young   +126 more
core   +1 more source

Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3 [PDF]

, 2017
Background: We have previously confirmed the importance of rat chromosome 3 (RNO3) genetic loci on blood pressure elevation, pulse pressure (PP) variability and renal pathology during salt challenge in the stroke-prone spontaneously hypertensive (SHRSP ...
Beattie, Wendy, Dashti, Mohammed, Dominiczak, Anna F., Graham, Delyth, Koh-Tan, H.H. Caline, McBride, Martin W., Mcclure, John, Wang, Ting, Young, Barbara   +8 more
core   +2 more sources