Results 111 to 120 of about 120,683 (236)

Systematic Comparison of High‐Fat Diet– and Streptozotocin‐Induced Prediabetic Obese C57BL/6J Mouse Models: A Sex‐Based Protocol Optimization Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9897-9918, November 2026.
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu   +7 more
wiley   +1 more source

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

open access: yesNew Phytologist, Volume 252, Issue 4, Page 1645-1659, November 2026.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source

Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice. [PDF]

open access: yesMol Ther, 2019
Matsuzaki Y   +6 more
europepmc   +1 more source

Coordination of drought‐adaptive root growth plasticity through auxin homeostasis by the ZmSPL12–ZmYUC5 module in maize

open access: yesNew Phytologist, Volume 252, Issue 4, Page 1526-1544, November 2026.
Proposed model of ZmSPL12‐mediated drought resistance through auxin regulation. Summary Climate change‐induced drought increasingly threatens global maize production. Drought‐adaptive root plasticity in maize depends on auxin signaling, yet how auxin homeostasis is dynamically tuned in response to water deficit remains unclear.
Hua Xu   +18 more
wiley   +1 more source

Genetic Contribution to Initial and Progressive Alcohol Intake Among Recombinant Inbred Strains of Mice. [PDF]

open access: yesFront Genet, 2018
Mulligan MK   +9 more
europepmc   +1 more source

Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 8643-8656, November 2026.
ABSTRACT Plant pathogens cause crop loss. Genetic resistance, through natural genetic diversity or engineered resistance, can be highly effective in protecting plants from infection. Genetic resistance from wild relatives of crops has been successfully introduced into crops to control pathogen infection.
Nathan Diplock, Jennifer D. Lewis
wiley   +1 more source

Sample size – not a one‐size‐fits‐all solution

open access: yes
The Journal of Physiology, EarlyView.
Kathryn L. Gatford
wiley   +1 more source

Endothelial Matrin‐3 Limits Cellular Senescence and Lipid Dysregulation to Protect Against Murine Atherosclerosis

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, Volume 16, Issue 10, Page 1958-1973, October 2026.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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