Results 131 to 140 of about 120,683 (236)
Abstract Infectious diseases remain a leading cause of morbidity and mortality among pediatric transplant recipients, despite significant advances in transplantation management. Vaccination is the most effective strategy to prevent infections; however, its efficacy is hindered in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT)
Valeria Casotti +35 more
wiley +1 more source
The genetic architecture of NAFLD among inbred strains of mice. [PDF]
Hui ST +15 more
europepmc +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Effects of housing density in five inbred strains of mice. [PDF]
Morgan JL +8 more
europepmc +1 more source
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang +17 more
wiley +1 more source
Bone morphology in 46 BXD recombinant inbred strains and femur-tibia correlation. [PDF]
Zhang Y +9 more
europepmc +1 more source
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin +4 more
wiley +1 more source
Hidden in plain sight: spike-wave discharges in mouse inbred strains. [PDF]
Letts VA, Beyer BJ, Frankel WN.
europepmc +1 more source
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source
Quantitative trait locus mapping of acute functional tolerance in the LXS recombinant inbred strains. [PDF]
Bennett B +7 more
europepmc +1 more source

