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Mouse inbred and congenic strains
1987Publisher Summary This chapter describes mouse inbred and congenic strains. Coisogenic strains are produced when a mutation occurs at one locus in a highly inbred strain. Then the original strain and the new strain differ only at the mutated locus, because with time the pair may begin to diverge at other loci as additional mutations occur and ...
Dagmar Klein, Jan Klein
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Endotoxin sensitivity of inbred mouse strains
Canadian Journal of Microbiology, 1973Inbred mouse strains show characteristic susceptibility to S. typhimurium infections. The sensitivity of the same strains to endotoxin is not parallel. While C3H/He J and C57B1/6J mice were highly susceptible to infection they showed more resistance to purified endotoxin than A/J, a mouse strain relatively resistant to infection.
Hugh G. Robson +2 more
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Reagin synthesis in inbred strains of rats
Journal of Allergy and Clinical Immunology, 1973Reaginic antibody synthesis after intraperitoneal immunization with ovalbumin in aluminium hydroxide gel (Al(OH)3) has been evaluated in BN, F344 and ACI inbred strains of rats and compared to that in outbred Wistar rats. Regardless of the dose of antigen employed (0.1 mg, 0.01 mg, 0.001 mg), BN inbred and Wistar outbred rats produced comparable ...
S. M. Murphey +3 more
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Impulsive choice in inbred strains of mice
Behavioural Processes, 2004When humans or non-humans are given a choice between receiving a sooner-smaller (SS) reinforcer, or a later-larger (LL) reinforcer, the choice of a SS reinforcer represents impulsive choice whereas the choice of a LL reinforcer represents self-controlled choice.
Takayuki Otobe, Junshiro Makino
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1979
Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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Inbred strains of a number of species of fish have been produced both by brother × sister mating and by gynogenesis. The latter can be induced artificially by using irradiated sperm and cold shock to induce parthenogenetic development. In this way a number of diploid gynogenetic plaice have been produced (Purdom and Lincoln, 1973).
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1979
Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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1979
According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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According to Fox (1974), the need for uniform research stocks of the rabbit was first recognised by Castle in 1922, in his studies of colour inheritance. However, the collection of inbred strains of rabbits now held at The Jackson Laboratory, which is easily the largest collection of such material in the world, was not initiated until 1929.
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Quiet mutations in inbred strains of mice
Trends in Molecular Medicine, 2007The year 2009 is the 100th anniversary of the founding of the first inbred strain of mouse, called DBA. During the last 100 years, inbred strains have proved their value for biomedical research and the number of such strains has mushroomed to over 450, each with different genotypic and phenotypic characteristics and useful for the study of disease and ...
Gareth Banks +3 more
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Lingual carcinogenesis in an inbred strain of hamsters
Journal of Oral Pathology & Medicine, 1978Abstract. Epidermoid carcinoma of the lateral border of the tongue can be induced in a standard strain of hamsters, applying DMBA in acetone after traumatizing the area with a root canal broach. Employing the same technique in an inbred strain of hamsters resulted in the more rapid development of carcinomas.
M. P. Marefat, Gerald Shklar
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Are Inbred Strains Suitable for Bio-assay?
Nature, 1954GRUNEBERG1 has directed attention to two properties of inbred strains which should counsel caution in their use for some experimental purposes: (1) They cannot be relied upon to remain constant in their heritable properties with the passage of time, and may diverge quite rapidly when split up into separate sub-strains and colonies.
Anne McLaren, Donald Michie
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