Results 31 to 40 of about 171,279 (298)

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]

open access: yes, 2009
Peer reviewedPublisher ...
Blizard, David A   +6 more
core   +3 more sources

Distribution of endogenous gammaretroviruses and variants of the Fv1 restriction gene in individual mouse strains and strain subgroups.

open access: yesPLoS ONE, 2019
Inbred laboratory mouse strains carry endogenous retroviruses (ERVs) classed as ecotropic, xenotropic or polytropic mouse leukemia viruses (E-, X- or P-MLVs).
Matthew Skorski   +4 more
doaj   +1 more source

Genetic analysis of cholesterol accumulation in inbred mice

open access: yesJournal of Lipid Research, 2001
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz   +3 more
doaj   +1 more source

Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]

open access: yes, 2017
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho   +3 more
core   +2 more sources

Experimental rat models of chronic allograft nephropathy: a review [PDF]

open access: yes, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

Recurrent Regional Allelic Imbalance in Chromosome 15 in Rat Endometrial Adenocarcinomas [PDF]

open access: yesCell Journal, 2010
Objective: Animals of the inbred BDII rat strain are genetically predisposed to endometrialadenocarcinomas (EAC) and can be used to model human cancer.
Ahmad Hamta, Farah Talebbeigy
doaj  

Phenotype and genetics of progressive sensorineural hearing loss (Snhl1) in the LXS set of recombinant inbred strains of mice. [PDF]

open access: yesPLoS ONE, 2010
Progressive sensorineural hearing loss is the most common form of acquired hearing impairment in the human population. It is also highly prevalent in inbred strains of mice, providing an experimental avenue to systematically map genetic risk factors and ...
Konrad Noben-Trauth   +3 more
doaj   +1 more source

Gene expression variation between mouse inbred strains

open access: yesBMC Genomics, 2004
Background In this study, we investigated the effect of genetic background on expression profiles. We analysed the transcriptome of mouse hindlimb muscle of five frequently used mouse inbred strains using spotted oligonucleotide microarrays.
Boer Judith M   +7 more
doaj   +1 more source

Genetic regulation of mouse liver metabolite levels. [PDF]

open access: yes, 2014
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and ...
Bennett, Brian J   +11 more
core   +1 more source

Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]

open access: yes, 2015
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO   +3 more
core   +1 more source

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