Results 51 to 60 of about 69,197 (298)

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load

Evolutionary Applications, 2019
Inbreeding depression, the deterioration in mean trait value in progeny of related parents, is a fundamental quantity in genetics, evolutionary biology, animal and plant breeding, and conservation biology.
Pirmin Nietlisbach, Stefanie Muff, Jane M. Reid, Michael C. Whitlock, Lukas F. Keller   +4 more
doaj   +1 more source

Potential benefit from using an identified major gene in BLUP evaluation with truncation and optimal selection [PDF]

, 1999
This study investigates the benefit of including information on an identified major gene in the estimation of breeding values in BLUP selection programmes. Selection for a quantitative trait is controlled by polygenes and a major locus with known effect.
Ricardo Pong-Wong, Grundy, B, Woolliams, JA, Villanueva, B., Pong-Wong, R.; id_orcid, Beatriz Villanueva, Villanueva, B, Pong-Wong, R, John A. Woolliams, Grundy, B., Woolliams, John, Brian Grundy   +11 more
core   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

INBREEDING AND INBREEDING DEPRESSION IN SLOVENIAN HOLSTEIN POPULATION [PDF]

Poljoprivreda, 2007
Analysis of inbreeding and inbreeding depression was done on the data of routine breeding value estimation for milk production data on Holstein population in Slovenia.
K. Potočnik, M. Štepec, J. Krsnik
doaj  

Veterinarian and breeder perspectives surrounding ovum pick‐up and intracytoplasmic sperm injection in mares: A survey study

Equine Veterinary Journal, EarlyView.
Abstract Background There is an ethical debate about the application of ovum pick‐up (OPU) and intracytoplasmic sperm injection (ICSI) in mares. Objectives To survey the opinions of equine veterinarians and breeders of sport horses on the ethics of using OPU–ICSI in mares. Study Design Cross‐sectional descriptive study.
Niamh Lewis, Jannie Spanner, Peter Daels, Juan Cuervo Arango, Monica Morganti, Pouya Dini, Kate Allen, Siobhan Mullan   +7 more
wiley   +1 more source

Exploring inbreeding depression in Brazilian Angus cattle population using pedigree and genomic data

Frontiers in Genetics
IntroductionInbreeding depression refers to the decline in performance caused by increased levels of inbreeding, which results from mating individuals with common ancestors.
Henrique A. Mulim, Gabriel S. Campos, Fernando Flores Cardoso, Hinayah Rojas de Oliveira   +3 more
doaj   +1 more source

Evolutionary genetics and consequences of inbreeding in sand lizards (Lacerta agilis) [PDF]

, 2021
Inbreeding is a well-known phenomenon in evolutionary and conservation biology. In the 19th century, Charles Darwin demonstrated the detrimental effects of inbreeding in plants, followed by over a century of extensive research including various ...
Bererhi, Badreddine
core   +1 more source

Monitoring Changes in Sperm Concentration and Quality Help Improve Captive Breeding Outcomes of the Endangered Amphibian Rawlinsonia littlejohni

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Amphibians are among the most threatened taxonomic groups, with many species experiencing rapid declines that have resulted in small, isolated populations vulnerable to inbreeding depression and reduced fertility. One major outcome of inbreeding is lowered fecundity, often linked to morphological changes in gametes.
Nadine Nolan, Anne Ibbotson, Natalie Calatayud, Matt W. Hayward, Alex Callen, Kaya Klop‐Toker, Rose Upton   +6 more
wiley   +1 more source