Results 61 to 70 of about 3,497,436 (306)

The causal relationship between anti-CD20 antibodies and endometrial cancer: a Mendelian randomization study

Discover Oncology
Purpose To determine the effects of anti-B cell surface marker CD20 antibody on the occurrence and progression of endometrial cancer to provide insights into clinical treatment in the future.
Jinqiu Su, Zhuang Li, Jianli Wang, Nairong Liu, Liyi Bao, Jiayuan Du, Yan Li, Yaojie Yu, He Wang   +8 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Cancer incidence and mortality among Ohio residents (Online); Other title: Title from OCISS reports index screen: Ohio cancer incidence and mortality report, an analysis of incidence and mortality data

, 2011
Annual; 1997/2001-; "The Ohio Department of Health [and] Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University."; Vol.

core  

reconhub/incidence: incidence version 1.4.1

, 2018
<p>This version introduces a re-written incidence constructor, support for text-based intervals, and a formalization of lists of <code>incidence_fit</code> classes.</p> incidence 1.4.1 BEHAVIORAL CHANGES <ul> <li>The &
Schumacher, Jakob, Thibaut Jombart, Zhian N. Kamvar, Jombart, Thibaut, Kamvar, Zhain, Pulliam, Juliet, Rich FitzJohn, Sarah Chisholm, Kamvar, Zhian N, Sangeeta Bhatia, Cai, Jun, Juliet Pulliam, Jakob Schumacher, Chisholm, Sarah, Fitzjohn, Rich, Jun Cai, Bhatia, Sangeeta   +16 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Resveratrol induces autophagy-dependent apoptosis in HL-60 cells

BMC Cancer, 2018
Background All known mechanisms of apoptosis induced by resveratrol act through cell cycle arrest and changes in mitochondrial membrane potential. It is currently unknown whether resveratrol-induced apoptosis is associated with other physiological ...
Yingying Fan, Jen-Fu Chiu, Jing Liu, Yan Deng, Cheng Xu, Jun Zhang, Guanwu Li   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Incidence-prevalence ratio and incidence-mortality ratio (with uncertainty bounds) by States/UTs in India, 2019.

, 2022
Incidence-prevalence ratio and incidence-mortality ratio (with uncertainty bounds) by States/UTs in India, 2019.
Damodar Sahu (3203208), Shashi Kant (3721432), Lakshmi P. V. M. (13113394), Chinmoyee Das (13113385), Vishnu Vardhana Rao Mendu (12667208), Elangovan Arumugam (13113391), Arvind Pandey (434795), Sanjay Mehendale (281610), Shobini Rajan (12360177), Pradeep Kumar (310858), Sanjay K. Rai (13113388), Shanta Dutta (185742), Dandu Chandra Sekhar Reddy (13113400), Arvind Kumar (227201), H. Sanayaima Devi (13113397), Sheela Godbole (628538)   +15 more
core   +1 more source

Molecular evidence of Tula virus in Microtus obscurus in the region of Yili, Xinjiang, China

BMC Infectious Diseases, 2019
Background Hantaviruses are important zoonotic pathogens, and they pose a profound risk to public health. So far, there has been no evidence showing that Tula virus (TULV), one species of hantavirus, is endemic in China.
Gang Guo, Baoping Guo, Xiran Wu, Yuanzhi Wang, Jianling Bao, Yuan Ren, Hongyu Li, Jun Li, Wenbao Zhang, Hua Yao   +9 more
doaj   +1 more source