Results 71 to 80 of about 3,512,284 (307)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Increasing incidence of thyroid cancer in shanghai, China, 1983-2007 [PDF]

, 2011
Increasing incidences of thyroid cancer were observed in some countries, like USA, UK, France, etc. Jointpoint regression was used to analyze the incidence of thyroid cancer in Shanghai, China, from 1983 to 2007.
Youxin Wang, Wei Wang
core   +2 more sources

Cancer-associated fibroblasts -derived Tenascin-C activates the Hippo/TAZ pathway to suppress ferroptosis and confer cisplatin resistance in esophageal cancer

Scientific Reports
This study aims to investigate the mechanistic role of fibronectin (TNC) secreted by cancer-associated fibroblasts (CAFs) and its impact on cisplatin (DDP) sensitivity in esophageal squamous cell carcinoma (ESCC).
Xueling Xiao, Zihao Dong, Meiheriban Aikebai, Saiyere Abulimiti, Yiliyaer Nuerrula, Aidiye Tiliwalidi, Mayinur Eli   +6 more
doaj   +1 more source

Molecular evidence of Tula virus in Microtus obscurus in the region of Yili, Xinjiang, China

BMC Infectious Diseases, 2019
Background Hantaviruses are important zoonotic pathogens, and they pose a profound risk to public health. So far, there has been no evidence showing that Tula virus (TULV), one species of hantavirus, is endemic in China.
Gang Guo, Baoping Guo, Xiran Wu, Yuanzhi Wang, Jianling Bao, Yuan Ren, Hongyu Li, Jun Li, Wenbao Zhang, Hua Yao   +9 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Incidence of Skin Cancer among Nagasaki Atomic Bomb Survivors [PDF]

, 1991
Of the 66, 276 Nagasaki atomic bomb survivors registered at the Scientific Data Center for the Atomic Bomb Disaster at the Nagasaki University School of Medicine, 140 were identified as having skin cancer from the records of 31 hospitals in Nagasaki City.
Mine, Mariko, Honda, Takeo, Sadamori, Naoki   +2 more
core  

Cancer incidence and mortality in France over the period 1980-2005. [PDF]

, 2008
BACKGROUND: The objective of this study was to provide updated estimates of national trends in cancer incidence and mortality for France for 1980-2005. METHODS: Twenty-five cancer sites were analysed.
Belot, A, Troussard, Xavier,, Bara, S, Hédelin, G, Raverdy, Nicole, Daubisse, L, Collignon, A, Arveux, Patrick, Trétarre, B, Faivre, Jean, Chérié-Challine, Laurence, Velten, M., Grosclaude, P, Colonna, Marc, Delafosse, Patricia, Monnereau, A, Benhamou, Ellen, Bovet, Martine, Molinié, F, Janoray, I, Bouvier, Anne Marie, Launoy, G, Grosclaude, Pascale, Bara, Simona, Monnereau, Alain, A., Troussard, Xavier, X., Le Stang, N, Maynadié, Marc, Janoray, Inès, Daubisse, Laetitia, Delafosse, P, Estève, J, Faivre, J, Monnereau, Alain,, Esteve, Jaume, Schvartz, C, Trétarre, Brigitte, Colonna, M, Bovet, M, Binder-Foucard, F, Bouvier, A-M, Hédelin, Guy, Collignon, Anne, Maynadié, M, Molinié, Florence, Remontet, L, Buemi, A, Belot, Aurélien, Schvartz, Claire, Launoy, Guy, Jougla, Eric, Danzon, Arlette, Troussard, X, Bossard, N, Guizard, A-V, Arveux, P, Jougla, E, Le Stang, Nolwenn, Benhamou, E, Raverdy, N, Binder-Foucard, Florence, Danzon, A, Velten, M, Guizard, Anne Valérie, Chérié-Challine, L, Remontet, L., Buemi, Antoine, Bossard, Nadine   +67 more
core   +1 more source