Results 91 to 100 of about 2,197,479 (275)
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Gap soliton formation by nonlinear supratransmission in Bragg media
, 2003 A Bragg medium in the nonlinear Kerr regime, submitted to incident cw-radiation at a frequency in a band gap, switches from total reflection to transmission when the incident energy overcomes some threshold.
A. Spire +15 more
core +3 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground While DNA methylation (DNAm)‐based algorithms of aging show promise for predicting age‐related diseases, their comparative utility for incident cardiovascular disease (CVD) remains underexplored.
Xian Cui +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Continuity of Operations in Newborn Screening: Lessons Learned from Three Incidents
International Journal of Neonatal ScreeningThree incidents that impacted two US newborn screening (NBS) programs highlight the importance of contingency planning for the continuity of operations (COOP).
M. Christine Dorley +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Pan Am flight 103 investigation and lessons learned
Aviation, 2009 On 21 December 1988, one of the most tragic incidents in the history of civil aviation took place. But the lessons of that tragic day and the impact of “Pan Am 103” or “Lockerbie” remain valuable and deserve attention. Santrauka 1988 m. gruodžio 21
Sergey Ushynskyi
doaj +1 more source