Results 61 to 70 of about 654,333 (264)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Analysis of Mechanical Response of Epoxy Asphalt-Repaired Pavement in Pothole Interface on Steel Bridge Deck under Coupled Temperature-Dynamic Loading

open access: yesBuildings
The persistence of pothole maintenance represents an enduring challenge. Past studies have largely concentrated on the materials and techniques used for remediation, with a lack of attention given to the pothole interface.
Yizhou Zhuang, Kai Liu, Xiaoli Zhan
doaj   +1 more source

Incline Prevention Reinforcement Structure– Controlling Building Incline

open access: yesInternational Journal of Architecture and Urbanism, 2022
 By chance facto (disasters, botchery operation) Incline Prevention Reinforcement Structure–Controlling Building Incline is to prevent Building incline when Building incline is measured after Building construction is finished, And is also to prevent Building incline when designs Building. It setted the Incline Prevention Reinforcement plate and pile on
Won Song Rim, null Song In Chol
openaire   +1 more source

Extension of the critical inclination

open access: yes, 2011
The critical inclination is of special interest in artificial satellite theory. The critical inclination can maintain minimal deviations of eccentricity and argument of pericentre from the initial values, and orbits at this inclination have been applied ...
Baoyin, Hexi, Liu, Xiaodong, Ma, Xingrui
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Model Test Study on the Bearing Mechanism of Inclined Variable Cross-Section Piles Using Transparent Soil

open access: yesApplied Sciences
In view of the influence of the inclination and variable section on the pile stability and bearing capacity, this paper introduces particle image velocimetry (PIV) technology, and designs a transparent soil visualization model test.
Qiang Ma, Jianyu Li, Lin Liu, Xuesong Lu
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Proofs of Control of a Quadrotor and a Ground Vehicle Manipulating an Object

open access: yes, 2018
This paper focuses on the control of a cooperative system composed of an Unmanned Aerial Vehicle (UAV) and an Unmanned Ground Vehicle (UGV) manipulating an object.
Catoire, Laurent   +2 more
core   +1 more source

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