Results 81 to 90 of about 659,420 (290)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Search for Stellar Companions to Exoplanet Host Stars Using the CHARA Array

, 2008
Most exoplanets have been discovered via radial velocity studies, which are inherently insensitive to orbital inclination. Interferometric observations will show evidence of a stellar companion if it sufficiently bright, regardless of the inclination ...
Ellyn K. Baines, Habets G. M. H. J., Harold A. McAlister, Imbert M., Judit Sturmann, Laszlo Sturmann, Mitchell D. S., Nils H. Turner, Perryman M. A. C., Stephen T. Ridgway, Theo A. ten Brummelaar   +10 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Effects of the difference foot strike pattern on the plantar pressure during uphill and downhill running

Frontiers in Sports and Active Living
The purpose of this study was to clarify the effects of foot strike patterns on plantar pressure distribution during uphill, level, and downhill running.
Yoshiki Horiguchi, Yoshiki Horiguchi, Hiroaki Noro, Keiichiro Hata, Yohei Yamazaki, Atsushi Kubota, Toshio Yanagiya, Toshio Yanagiya   +7 more
doaj   +1 more source

Hohmann spiral transfer with inclination change performed by low-thrust system [PDF]

, 2013
This paper investigates the Hohmann Spiral Transfer (HST), an orbit transfer method previously developed by the authors incorporating both high and low-thrust propulsion systems, using the low-thrust system to perform an inclination change as well as ...
Macdonald, Malcolm, Owens, Steven Robert
core  

Inferring the Inclination of a Black Hole Accretion Disk from Observations of its Polarized Continuum Radiation

, 2008
Spin parameters of stellar-mass black holes in X-ray binaries are currently being estimated by fitting the X-ray continuum spectra of their accretion disk emission.
Afshordi, Agol, Beckwith, Blandford, Brenneman, Chandrasekhar, Chandrasekhar, Charles, Davis, Davis, Davis, Ebisawa, Fragile, Fragile, Frank, Fryer, Fryer, Hjellming, Jeffrey E. McClintock, Krolik, Krolik, Krolik, Laor, Li, Li-Xin Li, Liu, McClintock, McClintock, McClintock, Miller, Misner, Narayan, Narayan, Noble, Novikov, Orosz, Orosz, Paczyński, Ramesh Narayan, Rees, Reynolds, Schnittman, Shafee, Shafee, Shafee, Shakura, Silverman, Swank, Vernet, Wagoner, Wald, Zahn   +51 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Kaldırma Kuvveti ve Yüzey Işınımının Eğik Bir Plakanın Çarpan Jet ile Soğutulmasına Etkilerinin Sayısal Olarak İncelenmesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi
Bu çalışmada, eğik bir plakanın tek bir slot jet ile soğutulmasında kaldırma kuvveti ve yüzeyler arası ışınımın taşınımla ısı transferine etkileri sayısal olarak incelenmiştir.
Buğra Sarper
doaj   +1 more source

The crown angulations and inclinations in Dravidian population with normal occlusion

Indian Journal of Dental Research, 2012
Background: There has always been a constant search for the definition of idealistic and realistic orthodontic treatment goals for different ethnic groups around the world.
Praveena Kannabiran, Gnanasagar J Thirukonda, Lodd Mahendra   +2 more
doaj   +1 more source