Results 61 to 70 of about 659,420 (290)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Applied SciencesIn view of the influence of the inclination and variable section on the pile stability and bearing capacity, this paper introduces particle image velocimetry (PIV) technology, and designs a transparent soil visualization model test.
Qiang Ma, Jianyu Li, Lin Liu, Xuesong Lu
doaj +1 more source
Geometric study of Lagrangian and Eulerian structures in turbulent channel flow [PDF]
, 2011 We report the detailed multi-scale and multi-directional geometric study of both evolving Lagrangian and instantaneous Eulerian structures in turbulent channel flow at low and moderate Reynolds numbers.
Pullin, D. I., Yang, Yue
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The effect of disk inclination on the Main Sequence of star forming galaxies
, 2016 We use the Sloan Digital Sky Survey (SDSS) database to explore the effect of the disk inclination angle on the derived star formation rate (SFR), hence on the slope and width of the Main Sequence (MS) relation for star-forming galaxies. We find that SFRs
Erfanianfar, G. +3 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A numerical exploration of Miranda's dynamical history
, 2013 The Uranian satellite Miranda presents a high inclination (4.338{\deg}) and evidences of resurfacing. It is accepted since 20 years (e.g. Tittemore and Wisdom 1989, Malhotra and Dermott 1990) that this inclination is due to the past trapping into the 3:1
Lemaitre, Anne +2 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Nature and regulation: Management of vineyards and orchards on terraces [PDF]
Urbani Izziv, 2006 The article deals with vineyards and terrace building as the best method of managing agricultural land on the steep slopes of the Primorska region. Data was gathered about the share of terraced vineyards and shares of vineyards according to inclination ...
Andreja Škvarč, Ivan Kodrič
doaj
On deriving p-mode parameters for inclined solar-like stars
, 2008 Thanks to their high quality, new and upcoming asteroseismic observations - with CoRoT, Kepler, and from the ground... - can benefit from the experience gained with helioseismology.
Appourchaux +18 more
core +1 more source