Results 131 to 140 of about 291,670 (308)
Journal of Traditional and Complementary Medicine, 2013 Excessive oxidative stress induced by reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive metabolites of carcinogens alters cellular homeostasis, leading to genetic/epigenetic changes, genomic instability, neoplastic ...
Jong Hun Lee +4 more
doaj +1 more source
Plant Polyphenols as Chemopreventive Agents for Lung Cancer
International Journal of Molecular Sciences, 2016 Lung cancer may be prevented by a diet rich in fruits and vegetables as they are enriched with dietary antioxidant polyphenols, such as flavonoids, proanthocyanidins, lignans, stilbenes, and phenolic acids.
M. Amararathna +2 more
semanticscholar +1 more source
Advanced Science, EarlyView.KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou +14 more
wiley +1 more source
Humphrey Center News: Spring 1989 v. 4, no. 1 [PDF]
, 1989 Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University +1 more
core
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma
Advanced Science, EarlyView.Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning +11 more
wiley +1 more source
Genomic alterations and precise medicine of esophageal squamous cell carcinoma
Journal of Bio-X Research, 2018 . Human cancer is a complex disease caused by the interaction of multiple genes and environmental factors. It is known that environmental factors such as smoking, drinking, and food carcinogens are implicated in the development of certain types of cancer
Qionghua Cui, BS +2 more
doaj +1 more source
Polymorphisms of CYP1A1 I462V and GSTM1 genotypes and lung cancer susceptibility in Mongolian [PDF]
, 2009 Aim: To study the genotype of cytochrome P450 1A1(CYP1A1) I462V and glutathions S-transferase M1( GSTM1) and the relationship of the genetic polymorphism of them with the susceptibility of lung cancer in Mongolia of China.
Fuhou Chang +6 more
core +1 more source
Advanced Energy and Sustainability Research, EarlyView.This study optimizes salinity gradient power generation using reverse electrodialysis (RED) by analyzing key operational parameters through factorial experiments and machine learning. Life cycle assessment reveals RED environmental impact and sustainability compared to other renewables, offering insights into future material choices and system ...
Younes Mohammadi +5 more
wiley +1 more source
Association Study of Polymorphism in CYP3A5 Gene with Bladder Cancer
Armaghane Danesh Bimonthly Journal, 2015 Aims and objectives: The environmental procarcinogen hypothesis of tumour pathogenesis proposes that many carcinogens require metabolic activation by drug metabolizing enzymes to form the proximate carcinogen.
m bakhtiari tajar +3 more
doaj
Aggregate, EarlyView.Herein, we present a twinkle‐light‐inspired “lighting‐up” bifunctional bacteriophage for fluorescence immunoassays via a spontaneous amino‐yne click reaction, and demonstrate its versatile potential for the highly sensitive detection of various targets, ranging from small molecules to pathogenic microorganisms, in complex samples.
Xiaoyi Lv +10 more
wiley +1 more source