Results 151 to 160 of about 268,946 (224)

The Insulin-Urothelial Axis: Evaluating Insulin Resistance as a Convergent Driver of Bladder Cancer Across Diverse Risk Factor Profiles. [PDF]

Int J Mol Sci
Tarantino G, Citro V, Imbimbo C, Crocetto F.   +3 more
europepmc   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

CarD-T: an automated pipeline for the nomination and analysis of potential human carcinogens. [PDF]

Carcinogenesis
O'Neill J, Reddy GA, Dhillon N, Tripathi O, Alexandrov L, Katira P.   +5 more
europepmc   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

Journal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira, Rogerio Salvini, Eloisa Dutra Caldas   +2 more
wiley   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Lung Cancer Screening and Prevention: Beyond Conventional Strategies in a Rapidly Changing Global Milieu. [PDF]

Am Soc Clin Oncol Educ Book
Gorría T, Marino N, Rubiano MAM, Salinas KE, Flores EJ, Mezquita L, Yang PC.   +6 more
europepmc   +1 more source

Bioelectrochemical single reactor for reductive and oxidative removal of trichloroethylene from contaminated groundwater

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Chlorinated aliphatic hydrocarbons such as trichloroethylene (TCE) are persistent groundwater contaminants due to improper disposal and low biodegradability. This work presents an innovative bioelectrochemical system for the integrated reductive/oxidative removal of TCE from contaminated water, implemented in a single tubular ...
Maria Presutti, Geremia Sassetto, Angela Marchetti, Giulia Simonetti, Marco Petrangeli Papini, Marco Zeppilli   +5 more
wiley   +1 more source

Association of second-hand tobacco smoking with liver cancer, and interaction with HBV infection in a Chinese population-based case-control study. [PDF]

Environ Epidemiol
Liu X, Baecker A, Wu M, Zhou JY, Jin ZY, Fang F, Jung SY, Mu L, He N, Qu W, Zhang X, Li L, Zhao JK, Zhang ZF.   +13 more
europepmc   +1 more source

A Framework to Establish Diet and Nutrition Competencies for Oral Health Care Education

Journal of Dental Education, EarlyView.
ABSTRACT Objective: To prevent and manage oral disease, oral health care practitioners (OHCPs) must provide dietary counseling based on nutrition science. OHCPs are often ill‐equipped to provide such counseling due to fragmented and inadequate dietary education, which is typically attributed to limited curricular time or appropriately qualified faculty.
Teresa A. Marshall, Michael Crowe, Riva Touger‐Decker   +2 more
wiley   +1 more source

Occupational exposure to cancer risk factors among health and social care workers in Europe: results from the Workers' Exposure Survey. [PDF]

Eur J Public Health
Khan MW, Vallbona-Vistós M, Cavet M, Vilahur N, Turner MC.   +4 more
europepmc   +1 more source