Results 161 to 170 of about 266,336 (265)

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer   +4 more
wiley   +1 more source

European Code Against Cancer, 5th edition - occupational exposures and cancer. [PDF]

open access: yesMol Oncol
Jochems SHJ   +17 more
europepmc   +1 more source

Impact of Environmental Carcinogens on Cancer Incidence: Long-term Exposure to Air Pollutants, Pesticides, and Industrial Chemicals as Cancer Risk Factors

open access: yes
Background: Environmental carcinogens, including air pollutants, pesticides, and industrial chemicals, are increasingly recognized as significant contributors to cancer incidence worldwide.
Shreem Vatsaraj
core  

Enhancement of Chronically-induced Breast Carcinogenesis by Combined Environmental and Dietary Carcinogens and Suppression by Dietary Agents

open access: yes, 2014
Most breast cancers occur sporadically due to long-term exposure to low-dose carcinogens present in our environment and diet. American lifestyles involve frequent exposures to smoke, polluted air, and high temperature-cooked meats comprising multiple ...
Pluchino, Lenora A.
core  

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara   +4 more
wiley   +1 more source

Hypoxic adaptation theory of cancer. [PDF]

open access: yesFront Cell Dev Biol
Kwan EK, Park J.
europepmc   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó   +3 more
wiley   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos   +4 more
wiley   +1 more source

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