Results 171 to 180 of about 266,336 (265)

Carcinogenicity prediction via multi-task learning of cross-organ representations with attention mechanisms. [PDF]

Brief Bioinform
Song Y, Choi H, Yoo S.
europepmc   +1 more source

Strategies to reverse treatment resistance in castration resistant prostate cancer (CRPC)

Prostate cancer (PC) growth and progression is usually dependent on androgens and androgen receptor (AR) signalling. Much research to date on metastatic castrate resistant prostate cancer (mCRPC) has focused on mechanisms of deregulated AR signalling. AR
Chandran, K
core  

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source

Prevalence and Etiopathogenic Profile of Oral Squamous Cell Carcinoma in Nonsmokers and Nondrinkers: Expanding Risk Determinants Beyond Tobacco Exposure. [PDF]

Diagnostics (Basel)
Stergiadou E, Louizakis A, Tatsis D, Antoniou A, Poulopoulos K, Poulopoulos A.   +5 more
europepmc   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case-control study. [PDF]

Occup Environ Med
Wan W, Vermeulen R, Portengen L, Olsson A, Schüz J, Bijoux W, Ahrens W, Barul C, Behrens T, Brüning T, Caporaso NE, Consonni D, Demers PA, Fabianova E, Fernández-Tardón G, Field J, Forastiere F, Foretova L, Ge CB, Gustavsson P, Janout V, Jöckel KH, Karrasch S, Kendzia B, Landi MT, Lissowska J, Mates D, McLaughlin J, Merletti F, Migliore E, Pándics T, Pohlabeln H, Radoï L, Richiardi L, Schejbalova M, Siemiatycki J, Świątkowska B, Wichmann HE, Zaridze D, Straif K, Kromhout H, Peters S.   +41 more
europepmc   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Genetic Polymorphisms and Antioxidant Reactions in Prostate Cancer. [PDF]

Int J Mol Sci
Kamiński P, Dróżdż-Afelt J, Gorzelańczyk EJ, Baszyński J, Tkaczenko H, Hromada M, Nuszkiewicz J, Woźniak A, Kurhaluk N.   +8 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

The Insulin-Urothelial Axis: Evaluating Insulin Resistance as a Convergent Driver of Bladder Cancer Across Diverse Risk Factor Profiles. [PDF]

Int J Mol Sci
Tarantino G, Citro V, Imbimbo C, Crocetto F.   +3 more
europepmc   +1 more source