Results 141 to 150 of about 268,946 (224)

A Systematic Review of Occupational Cancers in the Indian Sub-continent. [PDF]

Cureus
Bhardwaj R, Kumar N, Joshi S, Gupta A, Manna S.   +4 more
europepmc   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Carcinogenicity prediction via multi-task learning of cross-organ representations with attention mechanisms. [PDF]

Brief Bioinform
Song Y, Choi H, Yoo S.
europepmc   +1 more source

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source

Prevalence and Etiopathogenic Profile of Oral Squamous Cell Carcinoma in Nonsmokers and Nondrinkers: Expanding Risk Determinants Beyond Tobacco Exposure. [PDF]

Diagnostics (Basel)
Stergiadou E, Louizakis A, Tatsis D, Antoniou A, Poulopoulos K, Poulopoulos A.   +5 more
europepmc   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

Genetic Polymorphisms and Antioxidant Reactions in Prostate Cancer. [PDF]

Int J Mol Sci
Kamiński P, Dróżdż-Afelt J, Gorzelańczyk EJ, Baszyński J, Tkaczenko H, Hromada M, Nuszkiewicz J, Woźniak A, Kurhaluk N.   +8 more
europepmc   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto, Daniel Vitor de Souza, Gabriel Carvalhal de Aguiar, Ana Claudia Muniz Renno, Patricia Ramos Cury, Jean Nunes dos Santos, Rogerio Aparecido Dedivitis, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Occupational exposure to chlorinated solvents and lung cancer: results of the SYNERGY case-control study. [PDF]

Occup Environ Med
Wan W, Vermeulen R, Portengen L, Olsson A, Schüz J, Bijoux W, Ahrens W, Barul C, Behrens T, Brüning T, Caporaso NE, Consonni D, Demers PA, Fabianova E, Fernández-Tardón G, Field J, Forastiere F, Foretova L, Ge CB, Gustavsson P, Janout V, Jöckel KH, Karrasch S, Kendzia B, Landi MT, Lissowska J, Mates D, McLaughlin J, Merletti F, Migliore E, Pándics T, Pohlabeln H, Radoï L, Richiardi L, Schejbalova M, Siemiatycki J, Świątkowska B, Wichmann HE, Zaridze D, Straif K, Kromhout H, Peters S.   +41 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source