Results 141 to 150 of about 88,619 (213)

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma   +10 more
wiley   +1 more source

Synthetic biology for medical biomaterials

open access: yesInterdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu   +4 more
wiley   +1 more source

Racing toward the future of chronic hepatitis B management: Achieving functional cure and enhancing hepatocellular carcinoma surveillance through precision medicine

open access: yesInterdisciplinary Medicine, EarlyView.
Novel biomarker emergence plays a critical role in improving CHB management. Advances in sensitive detection methods, AI, and large‐scale data platforms have independently contributed to biomarkers while driving the development of multi‐omics approaches.
Yaru Shi, Rong Fan
wiley   +1 more source

Awareness of environmental carcinogens and cancer risk among Jordanians. [PDF]

open access: yesJ Egypt Public Health Assoc
El Gazzar WB   +9 more
europepmc   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li   +5 more
wiley   +1 more source

Gut microbial carcinogen metabolism: another avenue to cancer. [PDF]

open access: yesSignal Transduct Target Ther
Greten FR, Arkan MC.
europepmc   +1 more source

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal   +11 more
wiley   +1 more source

Evaluating the Genotoxicity and Mutagenicity of Food Contaminants: Acrylamide, Penitrem A, and 3‐Acetyldeoxynivalenol in Individual and Combined Exposure In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate the genotoxic effects of food contaminants exposure in human neuroblastoma SH‐SY5Y cells using the micronucleus (MN) assay and Ames test. Acrylamide (AA), penitrem A (PEN A), and 3‐acetyldeoxynivalenol (3‐ADON) were tested both individually and in combination.
Luna Bridgeman   +4 more
wiley   +1 more source

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