Results 81 to 90 of about 243,471 (265)
A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues
Advanced Science, EarlyView.Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan +12 more
wiley +1 more source
Is DNA methylation the new guardian of the genome?
Molecular Cytogenetics, 2017 Background It has been known for more than 100 years that aneuploidy is an essence of cancer. The question is what keeps the genome stable, thereby preventing aneuploidy. For the past 25 years, it has been proposed that p53 is the “guardian of the genome.
Robert M. Hoffman
doaj +1 more source
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention
Nature Reviews. Cancer, 2022 S. Hecht, D. Hatsukami
semanticscholar +1 more source
Prevalence of exposure to occupational carcinogens among farmers.
Rural and remote health, 2018 INTRODUCTION Farmers experience a range of carcinogenic exposures, including some pesticides, fuels, engine exhausts, metals, some organic solvents, silica, wood dusts and solar radiation.
Ellie Darcey +7 more
semanticscholar +1 more source
KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion
Advanced Science, EarlyView.Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li +12 more
wiley +1 more source
Quality in SportCancer is a disease of genetic material and develops as a result of the accumulation of gradually occurring genetic damage. The transformation of a normal cell into a cancer cell, known as neoplastic transformation, requires several gene mutations.
Maria Ciechacka
doaj +1 more source
Oxidative stress marker in oral cancer: A review.
Journal of Cancer Research and Therapeutics, 2016 Oxygen derived species such as hydrogen peroxide, superoxide anion radical, hydroxyl radical (OH-), and singlet oxygen are well known to be cytotoxic and have been implicated in the etiology of a wide array of human diseases, including cancer.
Payal Katakwar +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li +16 more
wiley +1 more source
Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility
Cadernos de Saúde PúblicaEpidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Ana Hatagima
doaj +2 more sources
Diagnostic and Therapeutic Potential of MicroRNAs in Lung Cancer
Cancers, 2017 Lung cancer is the leading cause of deaths resulting from cancer owing to late diagnosis and limited treatment intervention. MicroRNAs are short, non-coding RNA molecules that regulate gene expression post-transcriptionally by translational repression or
K. Inamura
semanticscholar +1 more source