Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A Case of Neutrophils with Bright Green Inclusion Bodies in Abdominal Drainage Fluid. [PDF]
Chen Z, Liang X, Wang Z.
europepmc +1 more source
Green Cytoplasmic Neutrophilic Inclusion Bodies in a Patient With Aspiration Pneumonia and Bowel Perforation. [PDF]
Wozniak PS, Rampon GL.
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Nonclassical inclusion bodies in
Menart Viktor +3 more
doaj +1 more source
Green Neutrophilic Inclusion Bodies. [PDF]
Yoshikawa T, Hagiwara S.
europepmc +1 more source
Neurodegenerative disease-associated inclusion bodies are cleared by selective autophagy in budding yeast. [PDF]
Folger A +4 more
europepmc +1 more source
STAINING OF THE INCLUSION BODIES OF TRACHOMA AND INCLUSION CONJUNCTIVITIS [PDF]
M J, GILKES, C H, SMITH, J, SOWA
openaire +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Modeling Cohen Syndrome in Phoenix Cells: VPS13B Loss Causes Organelle Stress, G1/S Delay, and Fibrillary Inclusion Bodies Formation. [PDF]
Morozova KN +5 more
europepmc +1 more source

