Results 151 to 160 of about 7,967 (189)
Some of the next articles are maybe not open access.
American Journal of Physical Medicine & Rehabilitation, 1990
Inclusion body myositis is a rare and slowly progressive myositis associated with cytoplasmic inclusions and fibrillar nuclear material. These histopathologic findings are of unknown significance. The clinical presentation of IBM has marked similarities to that of chronic polymyositis with proximal greater than distal weakness and muscle wasting more ...
D, Dumitru, M, Newell-Eggert
openaire +2 more sources
Inclusion body myositis is a rare and slowly progressive myositis associated with cytoplasmic inclusions and fibrillar nuclear material. These histopathologic findings are of unknown significance. The clinical presentation of IBM has marked similarities to that of chronic polymyositis with proximal greater than distal weakness and muscle wasting more ...
D, Dumitru, M, Newell-Eggert
openaire +2 more sources
Inclusion body myositis and paramyxoviruses
Human Pathology, 1991Inclusion body myositis (IBM) is a distinct type of muscle disease. The characteristic electron microscopic findings, intranuclear or intracytoplasmic inclusions composed of microtubular filaments, morphologically resemble paramyxovirus nucleocapsids.
M, Kallajoki +5 more
openaire +2 more sources
2007
Publisher Summary This chapter discusses inclusion body myositis (IBM). It is usually a slowly progressive myopathy that causes considerable morbidity but does not directly cause mortality. The lack of any effective treatments makes it a challenge to manage.
Michael R, Rose, Robert C, Griggs
openaire +2 more sources
Publisher Summary This chapter discusses inclusion body myositis (IBM). It is usually a slowly progressive myopathy that causes considerable morbidity but does not directly cause mortality. The lack of any effective treatments makes it a challenge to manage.
Michael R, Rose, Robert C, Griggs
openaire +2 more sources
Inclusion body myositis and myopathies
Annals of Neurology, 1995Preface Part I. Overview of Pathologic and Pathogenic Comparison Between Sporadic Inclusion-Body Myositis and Hereditary Inclusion-Body Myopathies: 1. Newest approaches to diagnosis and pathogenesis of sporadic inclusion-body myositis and hereditary inclusion-body myopathies, including molecular-pathologic similarities to Alzheimer disease Part II ...
R C, Griggs +6 more
openaire +2 more sources
Inclusion body myositis in twins
Neurology, 1998Sporadic inclusion body myositis (s-IBM) is characterized by late onset of slowly progressive weakness that involves the quadriceps and volar forearm muscles early in the course of the disease. There are hereditary forms of inclusion body myopathy (h-IBM) that histologically resemble s-IBM.
A A, Amato, R T, Shebert
openaire +2 more sources
Spectrum of Inclusion Body Myositis
Archives of Neurology, 1987The clinical, laboratory, and biopsy features are described for a large group of patients with inclusion body myositis (IBM) (15 men and four women; mean age, 63 years). A quantitative histopathologic analysis of muscle biopsy specimens revealed less fiber necrosis and endomysial and perivascular inflammation in IBM than in polymyositis (PM) and ...
S P, Ringel +4 more
openaire +2 more sources
Pathogenesis of inclusion body myositis
Current Opinion in Rheumatology, 2020Purpose of review To review the pathogenesis of inclusion body myositis (IBM). Recent findings IBM is an autoimmune disease. Multiple arms of the immune system are activated, but a direct attack on muscle fibers by highly differentiated T cells drives muscle destruction.
openaire +2 more sources
Genetics of inclusion‐body myositis
Muscle & Nerve, 2007AbstractSporadic inclusion‐body myositis (sIBM) is the most common acquired muscle disease in Caucasians over the age of 50 years. Pathologically it is marked by inflammatory, degenerative, and mitochondrial changes that interact in a yet‐unknown way to cause progressive muscle degeneration and weakness.
Needham, M. +2 more
openaire +2 more sources
Inclusion body myositis and myopathies
Current Opinion in Neurology, 1997Sporadic inclusion body myositis is a frequent, acquired, adult-onset vacuolar myopathy affecting proximal and distal muscles with a distinct, easily identifiable clinical pattern. Although its primary cause is still unknown, autoimmune, viral, and degenerative processes, alone or in combination, are being considered.
K, Sivakumar, M C, Dalakas
openaire +2 more sources
Update on Inclusion Body Myositis
Current Rheumatology Reports, 2018While sporadic inclusion body myositis (sIBM) is the most common acquired muscle disease after age 50, the pathogenesis of this disease is still poorly understood. In this review, we discuss our current state of knowledge in sIBM and provide an update on our current understanding of its pathophysiology and management.Lines of evidence in support of an ...
Duaa, Jabari +3 more
openaire +2 more sources