Results 141 to 150 of about 7,754,441 (252)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Transdermal microneedle delivery of rivaroxaban and its inclusion complex for enhanced anticoagulant therapy. [PDF]

RSC Adv
Khan WH, Khan IU, Munir R, Arshad MS, Irfan M, Usra, Zafar S, Rana SJ, Ali Shah SA, Khalid SH, Vandamme TF, Albekairi NA, Alshammari A.   +12 more
europepmc   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

β-Cyclodextrin-chitosan based carriers enhance the solubility and dissolution of baicalein through inclusion complex formation. [PDF]

Sci Rep
Malkawi R, Jarwan B, Alhawarri MB, Isawi IH, Banisalman K, Alghodran O, Al-Shdiefat Q.   +6 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Protocol to prepare inclusion complex-enhanced cannabinoid nano-micelles for behavioral pharmacology and in vivo neurophysiology in mice. [PDF]

STAR Protoc
Feng J, Page J, Chung L, He Z, Wang KH.
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

An Inclusion Complex of -Cyclodextrin-L-

, 2007
An inclusion host-guest complex between -cyclodextrin (-CD) and L-phenylalanine (LPhe) was investigated using H nuclear magnetic resonance spectroscopy and molecular docking ...
Jitraporn Vongsvivut, Nutsima Deechalao, Phenylalanine Nmr And, Pornthep Sompornpisut   +3 more
core  

Preparationof Konjac Glucomannan-Based Composite Films Loaded with Hydroxypropyl-β-Cyclodextrin/Hesperetin Inclusion Complex and Their Preservation Effect on Strawberries. [PDF]

Foods
Li G, Zhang J, Wu Y, Wang X, Lei X, Wei H, Hu Z, Weng Q, Zhang Q, Wen C, Sun Y, Ning Q.   +11 more
europepmc   +1 more source