Results 71 to 80 of about 3,117,048 (238)

Numerical analysis of a non-clamped dynamic thermoviscoelastic contact problem

, 2019
In this work we analyze a non-clamped dynamic viscoelastic contact problem involving thermal effect. The friction law is described by a nonmonotone relation between the tangential stress and the tangential velocity.
Bartman, Piotr, Bartosz, Krzysztof, Jureczka, Michał, Szafraniec, Paweł   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The zeros of monotone operators for the variational inclusion problem in Hilbert spaces

Journal of Inequalities and Applications, 2021
In this paper, we introduce a regularization method for solving the variational inclusion problem of the sum of two monotone operators in real Hilbert spaces.
Pattanapong Tianchai
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

OPTIMAL CONTROL PROBLEM OF SOME DIFFERENTIAL INCLUSION AND APPROXIMATION

Проблемы анализа, 2002
In this paper we present the optimal control problem governed by a variational inclusion with the monotone operator and a quadratic costfunctional. We apply standart Galerkin method to the approximation of the problem.
DEBINSKA-NAGORSKA A., JUST A., STEMPIEN Z., WOZNICA K.   +3 more
doaj  

Variational Inequalities Approaches to Minimization Problems with Constraints of Generalized Mixed Equilibria and Variational Inclusions

Mathematics, 2019
Multistep composite implicit and explicit extragradient-like schemes are presented for solving the minimization problem with the constraints of variational inclusions and generalized mixed equilibrium problems.
Lu-Chuan Ceng, Mihai Postolache, Ching-Feng Wen, Yonghong Yao   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Interaction between a crack and a soft inclusion [PDF]

With the application to weld defects in mind, the interaction problem between a planar-crack and a flat inclusion in an elastic solid is considered.
Erdogan, F., Xue-Hui, L.
core   +1 more source