Results 71 to 80 of about 7,330,350 (289)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

FOURIER PROBLEM FOR WEAKLY NONLINEAR EVOLUTION INCLUSIONS WITH FUNCTIONALS

Journal of Optimization, Differential Equations and Their Applications, 2019
The Fourier problem or, in other words, the problem without initial conditions for evolution equations and inclusions arise in modeling different nonstationary processes in nature, that started a long time ago and initial conditions do not affect on them
Mykola M. Bokalo, Iryna V. Skira
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

OPTIMAL CONTROL PROBLEM OF SOME DIFFERENTIAL INCLUSION AND APPROXIMATION

Проблемы анализа, 2002
In this paper we present the optimal control problem governed by a variational inclusion with the monotone operator and a quadratic costfunctional. We apply standart Galerkin method to the approximation of the problem.
DEBINSKA-NAGORSKA A., JUST A., STEMPIEN Z., WOZNICA K.   +3 more
doaj  

Generalized Yosida inclusion problem involving multi-valued operator with XOR operation

Demonstratio Mathematica
In this article, we study a generalized Yosida variational inclusion problem involving multi-valued operator with XOR operation. It is shown that the generalized Yosida variational inclusion problem involving multi-valued operator with XOR operation is ...
Iqbal Javid, Wang Yuanheng, Rajpoot Arvind Kumar, Ahmad Rais   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Inclusion Relationships Among Permutation Problems

Discrete Applied Mathematics, 1987
Let \(X=\{x_ 1,...,x_ n\}\) be a set of n elements. A permutation problem on X is a decision problem in NP which consists of determining whether there exists an n element permutation satisfying a set of ordering constraints expressed as collections of permutations of at most k elements of X.
Bovet, Daniel P, Panconesi, Alessandro
openaire   +2 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Volume Integral Equation Method Solution for Spheroidal Inclusion Problem. [PDF]

Materials (Basel), 2021
Lee J, Han M.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source