Results 101 to 110 of about 1,422,752 (285)

Student teacher attitudes and beliefs towards using ICT as part of inclusive practice: a 2008-2009 pilot survey [PDF]

open access: yes, 2012
In recent years there have been concerns in initial teacher education regarding the lack of attention given to developing students’ attitudes and beliefs to prepare them for inclusive education.
Beacham, N., McIntosh, K.
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Current Perspectives on Inclusive Education in the Czech Republic

open access: yes, 2017
This paper examines the academic literature describing the development of inclusive education programming within the Czech Republic after the Velvet Revolution. Interviews were conducted with special education professionals, who are researching potential
Langer, Moncia B.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Strategi Program Pendidikan Inklusif Dinas Pendidikan Pemuda dan Olahraga Kota Surakarta (Studi Tentang Kegiatan Pengadaan dan Peningkiatan Kapsitas Sumber Daya Manusia Pendidikan Inklusif) [PDF]

open access: yes, 2016
STRATEGI PROGRAM PENDIDIKAN INKLUSIF DINAS PENDIDIKAN PEMUDA DAN OLAHRAGA KOTA SURAKARTA (STUDI TENTANG KEGIATAN PENGADAAN DAN PENINGKATAN KAPASITAS SUMBER DAYA MANUSIA PENDIDIKAN INKLUSIF) Disusun Oleh : Arinda Anggit Pawestri Program Studi Ilmu ...
P, ARINDA ANGGIT
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Establishing a New Standard for Inclusion in the Classroom [PDF]

open access: yes, 2003
This paper challenges the generally accepted norm that special education is a place in which to put students rather than a process for supporting inclusion into the general education curriculum. The process of determining the Least Restricted Environment
Blessing, Carol   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Researching Writing Program Administration Expertise in Action: A Case Study of Collaborative Problem Solving as Transdisciplinary Practice [PDF]

open access: yes, 2019
Theorizing WPA expertise as problem-oriented, stakeholder-inclusive practice, we apply the twenty-first-century paradigm of transdisciplinarity to a campus WID Initiative to read and argue that data-driven research capturing transdisciplinary WPA methods
Serviss, Tricia, Voss, Julia
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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