Results 151 to 160 of about 6,627,008 (361)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Transgender Healthcare Teaching in the Undergraduate Medical School Curriculum [PDF]

, 2018
With increasing recognition of the diverse and specific needs of transgender individuals in a health care setting, lack of knowledge, poor attitudes and prejudice towards transgender patients can result in this population being afraid to access medical ...
Donaldson, A., Ewan, J., Frize, R., Sneddon, S.F.   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Dyadic Training of Communication Partners for Autistic Students: A Feasibility Study

Disabilities
Access to communication is a primary challenge affecting the education of Autistic students who use augmentative and alternative communication devices.
Eric J. Anderson, Emily Oehrtman, Nicholas Brown   +2 more
doaj   +1 more source

Meta-analysis of the relationship between teachers’ self-efficacy and attitudes toward inclusive education

, 2021
Akie Yada, Markku Leskinen, Hannu Savolainen, Susanne Schwab   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Inclusive Practices Outside of the United States: A Scoping Literature Review

Education Sciences
Regardless of differences in abilities, background, or citizenship, students have a right to effective education alongside their peers who do not have disabilities.
Eric J. Anderson, Emily Oehrtman, Elizabeth K. Cohara   +2 more
doaj   +1 more source

Battling the big one: LGBTQ inclusive art education during the Trump era [PDF]

, 2017
Recently, because of our new political atmosphere, there have been many attacks on lesbian, gay, bisexual, transgender, and queer, or LGBTQ+, individuals and communities. Even though there have been positive developments in the past few years, homophobia
Villalpando, Mark J
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Implementing Inclusive Design in Architectural Education and Design Practice

, 2020
Anna Szewczenko, Sylwia Widzisz-Pronobis
openalex   +1 more source