Results 121 to 130 of about 153,107 (265)

The effect of kinship on intraspecific competition in larvae of the poison frog Ameerega bassleri (Anura, Dendrobatidae)

open access: yesPhyllomedusa: Journal of Herpetology, 2008
According to inclusive fitness theory, cooperation between related individuals should ameliorate the effect of intraspecific competition. However, close relatedness is also thought to increase similarity between individuals and therefore increase the ...
Evan Twomey   +2 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Lifetime inclusive fitness effects of cooperative polygamy in the acorn woodpecker. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Koenig WD   +5 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Infrequent Cooperative Breeding in a Short-Lived Migratory Songbird, the Wilson’s Warbler

open access: yesBirds
Cooperative breeding, or helping behavior, has long been recognized in birds. An ignored dichotomy, however, separates the helping found in many individuals of some long-lived, sedentary species from the helping occasionally found in the territories of ...
William Gilbert
doaj   +1 more source

MATHEMATICS EDUCATION: STRATEGIES OF FITNESS FOR INCLUSIVE EDUCATION [PDF]

open access: yesRevista Gestão & Saúde, 2013
This research addresses the need and possibilities of adopting inclusive practices in school, today, as well as understanding what has been posted. Know to today that the school enrollment has been much discussion in the scientific community and we need ...
José Eduardo de Oliveira Evangelista Lanuti   +1 more
doaj  

Natural selection. IV. The Price equation

open access: yes, 2012
The Price equation partitions total evolutionary change into two components. The first component provides an abstract expression of natural selection. The second component subsumes all other evolutionary processes, including changes during transmission ...
Frank, Steven A.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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