Results 101 to 110 of about 974,747 (262)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Theory of Inclusive Fitness [PDF]

open access: yes, 2016
A review of Social Evolution and Inclusive Fitness Theory: An Introduction. By James A. R. Marshall. Princeton (New Jersey): Princeton University Press. $39.95. xix + 195 p.; ill.; index.
Queller, David C
core   +1 more source

The effect of kinship on intraspecific competition in larvae of the poison frog Ameerega bassleri (Anura, Dendrobatidae)

open access: yesPhyllomedusa: Journal of Herpetology, 2008
According to inclusive fitness theory, cooperation between related individuals should ameliorate the effect of intraspecific competition. However, close relatedness is also thought to increase similarity between individuals and therefore increase the ...
Evan Twomey   +2 more
doaj  

Digital Fitness and Sustainable Consumption: Understanding Consumer Motivations and Barriers [PDF]

open access: yesEuropean Journal of Interdisciplinary Studies
As digital fitness platforms and wellness technologies become the norm in modern health routines, understanding what impacts the user's engagement is key to creating inclusive, ethical and sustainable solutions.
Maria BRIANA, Ioannis KOSTAKIS
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

When do individuals maximize their inclusive fitness?

open access: yes, 2019
International audienceAdaptation is often described in behavioral ecology as individuals maximizing their inclusive fitness. Under what conditions does this hold and how does this relate to the gene-centered perspective of adaptation? We unify and extend
Lehmann, Laurent, Rousset, François
core   +1 more source

Physical fitness in preschool children : correlates and intervention effects [PDF]

open access: yes, 2011
Summary: Children’s physical fitness has decreased over the last decades. At the same time, the prevalence of overweight and obesity in children has increased dramatically. For public health, these trends are alarming because overweight and a decrease in
Bänteli-Niederer, Iris
core   +1 more source

Inclusive fitness and the major transitions in evolution [PDF]

open access: yesCurrent Opinion in Insect Science, 2019
Inclusive fitness theory is the leading framework for explaining the major transitions in evolution, whereby free-living subunits (e.g. cells, organisms) have cooperated to form new, higher-level units (e.g. organisms, eusocial societies). The theory has attracted considerable controversy.
openaire   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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