Results 91 to 100 of about 19,806 (267)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2016 A review of Social Evolution and Inclusive Fitness Theory: An Introduction. By James A. R. Marshall. Princeton (New Jersey): Princeton University Press. $39.95. xix + 195 p.; ill.; index.
Queller, David C
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Application of inclusive fitness theory.
, 2022 Fig 4 and S4 Fig presented an analysis of the simulations of the 1D model based on multilevel selection theory. Here, it is demonstrated that such simulations can also be analyzed from the perspective of inclusive fitness theory.
Rutger Hermsen (195605)
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hamilton's rule and its discontents [PDF]
, 2013 In an incendiary 2010 Nature article, M. A. Nowak, C. E. Tarnita and E. O. Wilson present a savage critique of the best known and most widely used framework for the study of social evolution, W. D. Hamilton’s theory of kin selection.
Birch, Jonathan
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Explorations in the Inclusive Fitness Movement: Community Voices & Visions
, 2021 This thesis explores the developing “inclusive fitness movement.” With Fitness4AllBodies at its center, whose explicit mission is to abolish the Fitness Industrial Complex, this thesis is based on interviews conducted with founder Justice Roe Williams ...
Sikorski, Bri
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Inclusive Fitness does not Impact the Survival Processing Effect
Animal Behavior and Cognition, 2019 Natural selection acts upon learning and memory processes, much as it does with other physical and behavioral characteristics. For example, numerous lines of inquiry using nonhuman species hypothesize adaptive specializations of Pavlovian conditioned ...
Mark A. Krause +5 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Inversión parental: una lectura desde la psicología evolucionista
Revista Latinoamericana en Ciencias Sociales, Niñez y Juventud, 2011 The aim of this paper is to present some contributions of evolutionary theory to the study of childrearing,for which it took like central axis the theory of parental investment and its role in the care, protection and guidanceof child development.
Eduardo Aguirre-Dávila
doaj
Inclusive Fitness 101: Math Not Required [PDF]
Trends in Ecology & Evolution, 2016 Inclusive fitness theory delivers a clever solution to the problem of altruism, especially the case of sterile worker castes in social insects. The idea behind the inclusive fitness theory is straight forward and contemporary: if you can somehow outsource reproduction, then you may reduce (or stop) personal reproduction.
openaire +1 more source