Results 51 to 60 of about 484,766 (271)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The stable roommates problem with ties [PDF]
, 2002 We study the variant of the well-known stable roommates problem in which participants are permitted to express ties in their preference lists. In this setting, more than one definition of stability is possible.
David F. Manlove +17 more
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Women's Acceptability of Misoprostol Treatment for Incomplete Abortion by Midwives and Physicians - Secondary Outcome Analysis from a Randomized Controlled Equivalence Trial at District Level in Uganda. [PDF]
PLoS ONE, 2016 OBJECTIVE:This study aimed to assess women´s acceptability of diagnosis and treatment of incomplete abortion with misoprostol by midwives, compared with physicians.
Amanda Cleeve +6 more
doaj +1 more source
Recursive Methods for Construction of Balanced N-ary Block Designs [PDF]
, 2005 2000 Mathematics Subject Classification: Primary 05B05; secondary 62K10.This paper presents a recursive method for the construction of balanced n-ary block designs.
Bousseboua, M., Gheribi-Aoulmi, Z.
core
An Efficient Block Circulant Preconditioner For Simulating Fracture Using Large Fuse Networks
, 2005 {\it Critical slowing down} associated with the iterative solvers close to the critical point often hinders large-scale numerical simulation of fracture using discrete lattice networks.
Batrouni G G +15 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Pirate plunder: game-based computational thinking using scratch blocks [PDF]
, 2018 Policy makers worldwide argue that children should be taught how technology works, and that the ‘computational thinking’ skills developed through programming are useful in a wider context. This is causing an increased focus on computer science in primary
Habgood, Jacob, Jay, Tim, Rose, Simon
core
Frame difference families and resolvable balanced incomplete block designs
, 2018 Frame difference families, which can be obtained via a careful use of cyclotomic conditions attached to strong difference families, play an important role in direct constructions for resolvable balanced incomplete block designs.
Costa, Simone, Feng, Tao, Wang, Xiaomiao
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source