Results 71 to 80 of about 115,467 (307)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Generation of Balanced Incomplete Blocks Designs Via Greedy Algorithm and (63,651,3,3,1) Design [PDF]

open access: yes, 2017
Optimal tasarımlar istatistiksel deney tasarımlarında önemli bir role sahiptir. Deney tasarımlarında sistematik değişimi azaltmak ve etki tahminlerinin doğruluğunu artırmak temel amaçtır. Bu amaçla deney tasarım bloklarından yararlanılır.
Erdoğan, Kemal Namık
core  

ESTIMACIÓN DE DATOS FALTANTES EN BLOQUES INCOMPLETOS BALANCEADOS CONECTADOS ESTIMACIÓN DE DATOS FALTANTES EN BLOQUES INCOMPLETOS BALANCEADOS CONECTADOS

open access: yesRevista Colombiana de Estadística, 2001
La presencia de datos faltantes en un experimento hace que se pierda la estructura original y en consecuencia la ortogonalidad del diseño original planteado.
Mendoza R. Henry, López P. Luis Alberto
doaj  

Intelligent Prediction of Ore Block Shapes Based on Novel View Synthesis Technology

open access: yesApplied Sciences
To address the problem of incomplete perception of limited viewpoints of ore blocks in future remote and intelligent shoveling-dominated mining scenarios, a method of using new view generation technology to predict ore blocks with limited view based on a
Lin Bi, Dewei Bai, Boxun Chen
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Author Correction: Chemical targets to deactivate biological and chemical toxins using surfaces and fabrics [PDF]

open access: yes, 2021
Correction to: Nature Reviews Chemistry https://doi-org.proxy.library.uu.nl/10.1038/s41570-021-00275-4, published online 05 May 2021. The originally published article contained an incomplete acknowledgements section, which now reads as: This work is part
Parker, Luke A.   +3 more
core  

Incomplete handwritten Dongba character image recognition by multiscale feature restoration

open access: yesHeritage Science
Incomplete handwritten Dongba character often appears in heritage documents and its recognition is significant for heritage and philology. However, all previous methods always suppose that a complete Dongba character is used as input, and thus fail to ...
Xiaojun Bi, Yanlong Luo
doaj   +1 more source

Uncovering Suspicious Activity From Partially Paired and Incomplete Multimodal Data

open access: yesIEEE Access, 2017
Multimodal data can be used to gain additional perspective on a phenomenon. For applications, such as security and the detection of suspicious activity, the need to aggregate and analyze data from multiple modes is vital.
Carter Chiu, Justin Zhan, Felix Zhan
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Incomplete split-plots in variety trials - based on a-designs

open access: yes, 2003
Incomplete split-plots based on a-designs are proposed as alternative to traditional split-plot designs. The purpose of the incomplete split-plot designs is to increase the efficiency of the treatment (whole plot factor) comparisons especially for ...
Kristensen, Dr. K.
core  

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