Results 81 to 90 of about 109,483 (265)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Identifying malignant mesothelioma by a pathological survey using the São Paulo state hospital cancer registry, Brazil [PDF]

Jornal Brasileiro de Pneumologia
Objective: To review the pathological diagnosis of possible cases and/or hidden cases of malignant mesothelioma (MM) between 2000 and 2012 using the Hospital-Based Cancer Registry database in the state of São Paulo, Brazil.
Fabiola Del Carlo Bernardi, Eduardo Algranti, Marisa Dolhnikoff, Clóvis Antônio Lopes Pinto, Ivanir Martins de Oliveira, Ester Nei Aparecida Martins Coletta, Eduardo Caetano Albino da Silva, Adauto José Ferreira Nunes, Donaldo Botelho Veneziano, Carolina Terra de Moraes Luizaga, Ricardo Luiz Lorenzi, Diego Rodrigues Mendonça e Silva, Thais Mauad   +12 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

L’ensemble lapidaire du service départemental d’Archéologie de l’Oise

In Situ
For several years now, the Oise Departmental Archaeology Service has been managing a conservation and study centre located in Creil. However, not all of the collections that would be appropriate for this centre have been deposited there yet.
Nicolas Bilot, Aymeric Laurent-Bougy, Cyril Meunier   +2 more
doaj   +1 more source

Augmented BIB Design-An Alternative Statistical Design in Germplasm Evaluation Trials

Journal of Horticultural Sciences, 2008
Randomized Block Design (RBD) is commonly employed to evaluate a set of germplasm accessions (test treatments) along with local checks. In such a trial, if the test treatments under evaluation are more in number and the availability of the seeds is ...
R Venugopalan, K R M Swamy, M K Chandraprakash   +2 more
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Fuzzy deep learning architecture for cucumber plant disease detection and classification

Journal of Big Data
This paper introduces a novel fuzzy deep convolutional neural network architecture for cucumber plant disease detection, contributing to precision farming in Industry 5.0.
Anas Bilal, Junaid Ali Khan, Abdulkareem Alzahrani, Khalid Almohammadi, Maha Alamri, Xiaowen Liu   +5 more
doaj   +1 more source