Results 171 to 180 of about 269,077 (284)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

A comprehensive dataset of United States federal procurement from 1979 to 2023. [PDF]

Sci Data
Omari A, Alansari N, Libgober B, Kaufman AR.   +3 more
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Healthy Homes: Repairs and Maintenance in Remote Northern Territory Housing. [PDF]

Int J Environ Res Public Health
Grealy L, Su JY, Thomas D.
europepmc   +1 more source

Passivation‐Induced Species Dynamics and Microstructural Evolution in Solid‐State Lithium–Sulfur Cathodes

Advanced Science, EarlyView.
The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma, Bairav S. Vishnugopi, Elif Pınar Alsaç, Matthew T. McDowell, Partha P. Mukherjee   +4 more
wiley   +1 more source

Provider Attribution in Medicare: Challenges and Solutions. [PDF]

Health Serv Res
Carlin CS, Feldman R, Jung J.
europepmc   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

RAB32-Linked Parkinson's Disease: Deep Phenotyping, MDSGene Literature Review, and Application of SynNeurGe Criteria. [PDF]

Mov Disord
Kleinz T, Cavallieri F, Borsche M, Toschi G, Valzania F, Fioravanti V, Valente EM, Mitrotti P, Avenali M, Zittel S, Born R, Matarazzo M, Di Fonzo A, Monfrini E, Radefeldt M, Santinelli L, Griebner N, Shambetova C, Brand M, Gabbert C, Blauwendraat C, Trinh J, Lohmann K, Beetz C, Bauer P, Brüggemann N, Global Parkinson's Genetics Program (GP2), Klein C.   +27 more
europepmc   +1 more source

Regioisomeric Effects on Enhancing p‐Type Characteristics of Self‐Assembled Molecules in Inverted Perovskite Solar Cells

Advanced Science, EarlyView.
Regioisomeric effects are a critical design parameter in self‐assembled monolyaer (SAM) engineering, underscoring their importance for optimizing buried interface properties and advancing the performance and stability of inverted perovskite solar cells.
Myeong‐Ho Hong, Sanwan Liu, Seong Chan Cho, Seung‐Joo Chang, Sang Uck Lee, Nam‐Gyu Park   +5 more
wiley   +1 more source

ChainShieldML an intelligent decentralized security framework for next generation wireless sensor networks. [PDF]

Sci Rep
Murala DK, Ahmad S, Ponnapalli VAS, Vuyyuru VA, Hitimana E.   +4 more
europepmc   +1 more source