Results 81 to 90 of about 1,095,657 (311)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Tensor-Based Uncoupled and Incomplete Multi-View Clustering
MathematicsMulti-view clustering demonstrates strong performance in various real-world applications. However, real-world data often contain incomplete and uncoupled views.
Yapeng Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KFCM-PSOTD : An Imputation Technique for Missing Values in Incomplete Data Classification
Cauchy: Jurnal Matematika Murni dan AplikasiData mining is a very important process for finding out the data interpretation. Data preprocessing is the crucial data mining steps. The existence of missing values in the data is one of the primary issues with data preprocessing. Generally, this can be
Muhaimin Ilyas +2 more
doaj +1 more source
Acta Universitatis Lodziensis. Folia Oeconomica, 2018 The problem of incomplete data and its implications for drawing valid conclusions from statistical analyses is not related to any particular scientific domain, it arises in economics, sociology, education, behavioural sciences or medicine.
Małgorzata Misztal
doaj +1 more source
On Incomplete XML Documents with Integrity Constraints
, 2010 We consider incomplete specifications of XML documents inthe presence of schema information and integrity constraints. We showthat integrity constraints such as keys and foreign keys affect consistencyof such specifications. We prove that the consistency
Libkin, Leonid +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
CoRe-Sleep: A Multimodal Fusion Framework for Time Series Robust to Imperfect Modalities
IEEE Transactions on Neural Systems and Rehabilitation EngineeringSleep abnormalities can have severe health consequences. Automated sleep staging, i.e. labelling the sequence of sleep stages from the patient’s physiological recordings, could simplify the diagnostic process.
Konstantinos Kontras +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source