Results 111 to 120 of about 2,336,721 (286)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Compound and Incorporation Constructionsas Combinations of Unexpandable Roots

open access: yesZeitschrift für Wortbildung
This paper offers definitions of the terms compound construction, compoundand incorporation constructionthat can be applied to all languages in the same way.
Martin Haspelmath
doaj   +1 more source

«ABKHAZIA... WAS FULL OF INTRIGUES»: THE POLITICAL HISTORY OF ABKHAZIA IN THE FIRST HALF OF XIX CENTURY IN «MEMORIES» G. I. PHILIPSON

open access: yesГуманитарные и юридические исследования, 2021
This article examines the original concept of the political history of Abkhazia in the first half of the XIX century which was reconstructed by means of qualitative analysis of a well-known narrative source - «Memories» by G. I. Philipson.
N. A. Trapsh
doaj  

Hybrid gold single crystals incorporating amino acids

open access: yes, 2016
Composite hybrid gold crystals are of profound interest in various research areas ranging from materials science to biology. Their importance is due to their unique properties and potential implementation, for example in sensing or in bio-nanomedicine ...
Chen, Linfeng   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

ABOUT STRESS EXPERIMENTS BY DEVELOPING / IMPROVING ANALYTICAL METHODS AND TECHNOLOGY OF DRUG SUBSTANCES AND MEDICINES

open access: yesРазработка и регистрация лекарственных средств, 2019
The main objectives of stress experiments and tests corresponding to them, and also stress experiments for preparation of solutions for check of system suitability of chromatographic systems are in detail considered.
N. A. Epshtein
doaj  

Effects of carbon incorporation on doping state of YBa2Cu3Oy

open access: yes, 2004
Effects of carbon incorporation on the doping state of YBa2Cu3Oy (Y-123) were investigated. Quantitative carbon analysis revealed that carbon could be introduced into Y-123 from both the precursor and the sintering gas.
A. Yamamoto   +17 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Fluorescence resonance energy transfer between organic dyes adsorbed onto nano-clay and Langmuir-Blodgett (LB) films

open access: yes, 2010
In this communication we investigate two dyes N,N' -dioctadecyl thiacyanine perchlorate (NK) and octadecyl rhodamine B chloride (RhB) in Langmuir and Langmuir-Blodgett (LB) films with or with out a synthetic clay laponite.
Arbeloa   +43 more
core   +1 more source

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